5-(4-Chlorophenyl)isoxazol-3-ol CAS 14723-58-1
| CAS No. | 14723-58-1 |
| Molecular Formula | C9H6ClNO2 |
| Molecular Weight | 195.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 5-(4-Chlorophenyl)isoxazol-3-ol (CAS 14723-58-1), a certified reference material (molecular formula C9H6ClNO2, MW 195.60 g/mol) for analytical method development and quality control.
The molecular framework of 5-(4-Chlorophenyl)isoxazol-3-ol (C9H6ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C9H6ClNO2 |
| Molecular Weight | 195.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorophenyl Standards
- 3-(3-Chlorophenyl)-5-hydroxyisoxazole (CAS 1354923-77-5)
- 3-(2-Chlorophenyl)-5-hydroxyisoxazole (CAS 1354938-66-1)
- 2-(3-Chlorophenyl)oxazol-5(4H)-one (CAS 75152-20-4)
- 2-(4-Chlorophenyl)oxazol-5(4H)-one (CAS 22887-53-2)
- 3-(2-Chlorophenyl)isoxazol-5(4H)-one (CAS 27025-73-6)
- 3-(3-Chlorophenyl)isoxazol-5(4H)-one (CAS 51725-85-0)
- 3-(4-Chlorophenyl)-5-hydroxyisoxazole (CAS 862588-73-6)
- 3-(4-Chlorophenyl)isoxazol-5(2H)-one (CAS 467253-22-1)
Recommended Standards
- 6-Chloro-1H-indole-4-carboxylic acid (CAS 1448260-43-2)
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- 1-(6-Chlorobenzo[d]oxazol-2-yl)ethanone (CAS 1519913-88-2)
- 6-bromo-3-ethyl-2-mercaptoquinazolin-4(3H)-one (CAS 18009-16-0)
- Actagardin (CAS 59165-34-3)
- 4-(2-Acetyl-3-methylbenzofuran-5-yl)furan-2(5H)-one (CAS 3447-79-8)
- 1,1'-Bis(2-ethoxy-2-oxoethyl)-[4,4'-bipyridine]-1,1'-diium bromide (CAS 75539-74-1)
- 3-(3-chlorofuran-2-yl)prop-2-enoic acid (CAS 100949-21-1)
- (3S)-3-ethoxypyrrolidine (CAS 143943-75-3)
- 3-[[(2-Methoxyethoxy)methyl Erythromycin A Oxime Chloride (CAS 151750-47-9)
- 6-Shogaol (CAS 555-66-8)
- 1,3-Diethyl-1H-pyrazole-5-carbaldehyde (CAS 1352537-65-5)
- Cyclolinopeptide B (CAS 193139-41-2)
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