4-Bromo-4,4-difluorobutyricacid CAS 147345-36-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-Bromo-4,4-difluorobutyricacid.

CATO supplies 4-Bromo-4,4-difluorobutyricacid (CAS 147345-36-6), a certified reference material (molecular formula C4H5BrF2O2, MW 202.98 g/mol) for analytical method development and quality control.

4-Bromo-4,4-difluorobutyricacid (C4H5BrF2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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