4-(Trifluoromethyl)-1,2-dihydro-2-oxo-6-p-tolylpyridine-3-carbonitrile CAS 147381-60-0
| CAS No. | 147381-60-0 |
| Molecular Formula | C15H10F3NO |
| Molecular Weight | 277.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 4-(Trifluoromethyl)-1,2-dihydro-2-oxo-6-p-tolylpyridine-3-carbonitrile.
4-(Trifluoromethyl)-1,2-dihydro-2-oxo-6-p-tolylpyridine-3-carbonitrile (CAS 147381-60-0), molecular formula C15H10F3NO and molecular weight 277.24 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-(Trifluoromethyl)-1,2-dihydro-2-oxo-6-p-tolylpyridine-3-carbonitrile (C15H10F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-(Trifluoromethyl)-1,2-dihydro-2-oxo-6-p-tolylpyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H10F3NO |
| Molecular Weight | 277.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Trifluoromethyl Standards
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- 2-(3-(Trifluoromethyl)phenyl)isoindolin-1-one (CAS 1374223-02-5)
- 2-Phenyl-6-(trifluoromethyl)imidazo[1,2-a]pyridin-8-amine (CAS 1707727-56-7)
- 1-Phenyl-5-(trifluoromethyl)-1H-indazol-3-amine (CAS 61272-73-9)
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Recommended Standards
- 3-(Benzylamino)-2-cyano-5-(trifluoromethyl)pyridine (CAS 1449117-52-5)
- 1-(Bromomethyl)-1-(3,3-dimethylbutoxy)cyclohexane (CAS 1495432-32-0)
- (R)-2-methoxy-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide (CAS 1391496-87-9)
- 3,3,3-Trifluoro-N-(1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl)propanamide (CAS 1705803-20-8)
- 1-(2-Isothiocyanatoethoxy)-2-methoxybenzene (CAS 887405-52-9)
- 219959-87-2 9-(4'-Hydroxyaminophenyl)-9H-pyrido[3,4-b]indole Hydroxyaminophenylnorharman N-Hydroxy-4-(9H-pyrido[3,4-b]indol-9-yl)benzenamine (CAS 219959-87-2)
- 3-(3-Ethyl-1,2,4-oxadiazol-5-yl)benzonitrile (CAS 1421261-77-9)
- N-cyclopropyl-6-methyl-5-((methylamino)methyl)pyridin-2-amine (CAS 1355219-10-1)
- 6-((6-Methoxy-3,7,7-trimethyloct-2-en-1-yl)oxy)-2,3-dihydrobenzofuran (CAS 51079-81-3)
- 8-Bromo-3,4-dihydro-1H-benzo[b]azepin-5(2H)-one (CAS 851045-03-9)
- Lubiprostone Impurity 32 (CAS CATO-C4X-113632)
- Cgp 71683 (CAS 192321-23-6)
- (6-Bromo-2-chloro-3-ethoxyphenyl)methanol (CAS 2386676-58-8)
- Mast Cell Degranulating Peptide (CAS 83856-13-7)
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