3,4,5-Trimethoxyphenylisocyanide CAS 147492-94-2
| CAS No. | 147492-94-2 |
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3,4,5-Trimethoxyphenylisocyanide is closely related to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3,4,5-Trimethoxyphenylisocyanide (CAS 147492-94-2) is a high-purity analytical reference standard with the molecular formula C10H11NO3 and a molecular weight of 193.20 g/mol.
3,4,5-Trimethoxyphenylisocyanide (C10H11NO3) contains an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3,4,5-Trimethoxyphenylisocyanide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H11NO3 |
| Molecular Weight | 193.20 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Recommended Standards
- Ethyl 2-oxo-2-(phenylamino)acetate (CAS 1457-85-8)
- 2,4,5-Trimethoxybenzonitrile (CAS 14894-77-0)
- Ethyl 3-amino-4-cyano-1-methyl-1H-pyrrole-2-carboxylate (CAS 145162-36-3)
- 2-Amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)ethan-1-one (CAS 1495333-95-3)
- Ethyl 5-(3-fluorophenoxy)pentanoate (CAS 1443329-01-8)
- (3-Chloro-4-fluorophenyl)(3,4-difluorobenzyl)sulfane (CAS 1443352-16-6)
- 3-((Cyclopropylmethoxy)methyl)-5,6,7,8-tetrahydro-4H-[1,2,3]triazolo[1,5-a][1,4]diazepine (CAS 1422135-94-1)
- 1-BROMO-2,6-DIFLUOROBENZENE 2,6-DIFLUOROBROMOBENZENE 2-BROMO-1,3-DIFLUOROBENZENE 64248-56-2 BC002389 BENZENE, 2-BROMO-1,3-DIFLUORO (CAS 64248-56-2)
- 2-Methyl-4-(3-pyridinyloxy)aniline dihydrochloride (CAS 1185302-52-6)
- 1-{[3-(4-Methoxyphenyl)-1,2,4-oxadiazol-5-yl]methyl}piperazine hydrochloride (CAS 1052553-32-8)
- 2-Methyl-N-(1-(4-(methylthio)phenyl)ethyl)propan-1-amine (CAS 1019532-13-8)
- 2-(Cyclohexylmethoxy)-1-ethanamine (CAS 200400-14-2)
- 7,7-Dimethyl-6,7,8,9-tetrahydro-5h-benzo[7]annulen-5-amine (CAS 1344230-73-4)
- D-Thr5-Tirzepatide (CAS CATO-CPTD788926)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com