1-(2-Ethoxyphenoxy)-3-(methylamino)propan-2-ol CAS 14754-63-3
| CAS No. | 14754-63-3 |
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-(2-Ethoxyphenoxy)-3-(methylamino)propan-2-ol (CAS 14754-63-3), molecular formula C12H19NO3 and molecular weight 225.28 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(2-Ethoxyphenoxy)-3-(methylamino)propan-2-ol (C12H19NO3) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(2-Ethoxyphenoxy)-3-(methylamino)propan-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H19NO3 |
| Molecular Weight | 225.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Nitrogen Atoms | 1 |
Related Ethoxyphenoxy Standards
- 2-(4-Ethoxyphenoxy)propanehydrazide (CAS 727704-73-6)
- 2-(4-Ethoxyphenoxy)-2-methylpropanoic acid (CAS 154548-95-5)
- 4-(2-Ethoxyphenoxy)butanoic acid (CAS 721416-38-2)
- 3-(4-Ethoxyphenoxy)-2,2-dimethylpropan-1-amine (CAS 1225686-05-4)
- 3-(2-Ethoxyphenoxy)piperidine (CAS 902837-36-9)
- 3-(3-Ethoxyphenoxy)piperidine (CAS 946714-65-4)
- 4-(2-Ethoxyphenoxy)piperidine (CAS 420137-19-5)
- 2-(2-Ethoxyphenoxy)aniline (CAS 946714-34-7)
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