1-(Chloromethyl)-2-fluoro-4-methylbenzene CAS 147541-99-9
| CAS No. | 147541-99-9 |
| Molecular Formula | C8H8ClF |
| Molecular Weight | 158.60 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
1-(Chloromethyl)-2-fluoro-4-methylbenzene (CAS 147541-99-9), molecular formula C8H8ClF and molecular weight 158.60 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine/chlorine substitution, an aromatic ring system, 1-(Chloromethyl)-2-fluoro-4-methylbenzene is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 158.60 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures 1-(Chloromethyl)-2-fluoro-4-methylbenzene under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H8ClF |
| Molecular Weight | 158.60 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloromethyl Standards
- 2-(Chloromethyl)-1-fluoro-3-methylbenzene (CAS 1182356-79-1)
- 1-(chloromethyl)-4-(fluoromethyl)benzene (CAS 1182356-92-8)
- 1-(Chloromethyl)-3-fluoro-5-methylbenzene (CAS 1214361-65-5)
- 4-(Chloromethyl)-2-fluoro-1-methylbenzene (CAS 147542-00-5)
- 1-(Chloromethyl)-2-(fluoromethyl)benzene (CAS 2383969-57-9)
- 1-(Chloromethyl)-3-fluoro-2-methylbenzene (CAS 340984-89-6)
- 1-(chloromethyl)-4-fluoro-2-methylbenzene (CAS 80141-92-0)
- 2-(chloromethyl)-1-fluoro-4-methylbenzene (CAS 64977-31-7)
Recommended Standards
- 4-Chloro-2-ethyl-1-fluorobenzene (CAS 1369889-05-3)
- 2-Chloro-5-fluoro-1,3-dimethylbenzene (CAS 14994-16-2)
- 1-Chloro-2,3-dimethyl-5-fluorobenzene (CAS 1207091-16-4)
- 1-Chloro-2,3-dimethyl-4-fluorobenzene (CAS 1805952-33-3)
- Atomoxetine Impurity 38 (CAS 29869-74-7)
- 6-Methylisoxazolo[5,4-d]pyrimidin-3-amine (CAS 1171935-86-6)
- Glycylasparagine (CAS 32729-21-8)
- Benzyl 8,8-dimethyl-1-oxa-4,9-diazaspiro[5.5]undecane-4-carboxylate (CAS 2888531-29-9)
- 11D-582 400074-80-8 7-methoxy-5-methyl-2-phenylmethanesulfonyl-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 400074-80-8)
- 1,2- Benzenedic Arboxylic Acid, Dipentylest Er, Branched And Linear (CAS CATO-LPAE111743-HE)
- 2,3-Diamino-5-(2-hydroxyethyl)-6-methylpyrimidin-4(3H)-one (CAS 95095-45-7)
- 5-Ethyl-4-(hydroxymethyl)isoxazole-3-carboxylic acid (CAS 1134334-00-1)
- 1-(1,1-Difluorobutyl)-4-fluorobenzene (CAS 1099598-07-8)
- Semaglutide impurity 71 (CAS CATO-C4X-222671)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com