Paliperidone Impurity 24 CAS 147687-17-0
| CAS No. | 147687-17-0 |
| Molecular Formula | C18H17ClN2O2 |
| Molecular Weight | 328.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Paliperidone Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Paliperidone Impurity 24 (CAS 147687-17-0, C18H17ClN2O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Paliperidone Impurity 24 (C18H17ClN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 328.79 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C18H17ClN2O2 |
| Molecular Weight | 328.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Paliperidone Standards
- Paliperidone Impurity 70 (CAS CATO-C4X-172470)
- Paliperidone Impurity 148 (CAS CATO-C4X-1724148)
- Paliperidone Impurity 72 (CAS CATO-C4X-172472)
- Paliperidone Impurity 49 (CAS 1008796-22-2)
- Paliperidone Impurity 25 (CAS CATO-C4X-172425)
- Paliperidone Impurity 94 (CAS CATO-C4X-172494)
- Paliperidone Impurity 92 (CAS CATO-C4X-172492)
- Paliperidone Impurity J (CAS 2379324-96-4)
Recommended Standards
- Metoclopramide impurity 47 (CAS CATO-C4X-141547)
- Tolvaptan Impurity 11 (CAS 137977-97-0)
- Metoclopramide Impurity 100 (CAS CATO-C4X-1415100)
- Lornoxicam Impurity 36 (CAS CATO-C4X-201636)
- Moxifloxacin Impurity 197 (CAS CATO-C4X-1074197)
- Tadalafil impurity 96 (CAS CATO-C4X-108796)
- relugolix Impurity 93 (CAS CATO-C4X-242993)
- 5-(Difluoromethyl)pyrrolidin-2-one (CAS 70994-03-5)
- 52947-05-4 Benzoyl chloride-(carbonyl-13C) Benzoyl chloride-|A-13C (CAS 52947-05-4)
- 5-Bromo-2-chloro-6-methylpyridine-3-carbaldehyde (CAS 1935331-10-4)
- 6'-Amino-3'H-spiro[cyclopentane-1,1'-isobenzofuran]-3'-one (CAS 217196-63-9)
- 5,7-Dimethoxyquinolin-4-amine (CAS 1249443-89-7)
- 2-(Methylsulfanyl)-4-(2,4,5-trichlorophenoxy)quinazoline (CAS 477845-94-6)
- Semaglutide Impurity 164 (CAS CATO-C4X-2226164)
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