Azetidin-3-yl(4-(trifluoromethyl)piperidin-1-yl)methanone CAS 1478039-79-0
| CAS No. | 1478039-79-0 |
| Molecular Formula | C10H15F3N2O |
| Molecular Weight | 236.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Azetidin-3-yl(4-(trifluoromethyl)piperidin-1-yl)methanone.
Azetidin-3-yl(4-(trifluoromethyl)piperidin-1-yl)methanone (CAS 1478039-79-0), molecular formula C10H15F3N2O and molecular weight 236.23 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Azetidin-3-yl(4-(trifluoromethyl)piperidin-1-yl)methanone (C10H15F3N2O) is characterized by an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C10H15F3N2O |
| Molecular Weight | 236.23 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Azetidin Standards
- 2-(Azetidin-1-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 1389946-63-7)
- 2-(Azetidin-3-yl)-3-chloro-5-(trifluoromethyl)pyridine (CAS 1781241-45-9)
- 1-(4-(Azetidin-3-yl)piperazin-1-yl)-2,2,2-trifluoroethanone (CAS 1252779-86-4)
- 1-(Azetidin-3-ylcarbonyl)-4-cyclobutyl-1,4-diazepane (CAS 1238877-60-5)
- 8-(Azetidin-3-yloxy)-5-chloroquinoline (CAS 1219981-48-2)
- 5-(azetidin-1-yl)-2-(piperidin-3-yl)-2,3-dihydropyridazin-3-one (CAS 1803587-53-2)
- Methyl 4-(azetidin-3-yloxy)-1-methyl-6-oxo-1,6-dihydropyridine-3-carboxylate (CAS 1864074-78-1)
- 1-(Azetidin-3-ylsulfonyl)indoline (CAS 1803591-38-9)
Recommended Standards
- 3-methyl-7-(trifluoromethyl)-3,4-dihydro-1H-quinoxalin-2-one (CAS 146741-08-4)
- 3H,3'H-5,5'-Bibenzo[d][1,2,3]triazole (CAS 15805-13-7)
- ethyl 1-[(3-methyl-1,2,4-oxadiazol-5-yl)methyl]-1H-pyrazole-4-carboxylate (CAS 1461704-82-4)
- 4-((4-Nitrophenyl)diazenyl)morpholine (CAS 161265-61-8)
- 5-(n-(2-Bromo-5-methylphenyl)sulfamoyl)-2-chlorobenzoic acid (CAS 554405-81-1)
- 3,3'-(1,4-phenylenebis(azanediyl))bis(5,5-dimethylcyclohex-2-enone) (CAS 78431-57-9)
- Benzyltriphenylphosphine (CAS 1449-46-3)
- 3-Methylsulfonyl-2,3',4',5-tetrachlorobiphenyl (CAS 116807-53-5)
- 5-Chloromethyl-2-methyl-pyridine-4-yliamine hydrochloride (CAS 1186195-03-8)
- (4S,4′S)-2,2′-[5-(1,1-Dimethylethyl)-1,3-phenylene]bis[4,5-dihydro-4-(1-methylethyl)oxazole] (CAS 1056697-75-6)
- 2-(4-Ethoxyphenyl)-6-methylquinoline-4-carbohydrazide (CAS 438227-02-2)
- ivDde-Lys(Fmoc)-OH (CAS 1446752-60-8)
- Methyl (S)-2-acetamido-3-(2,3,6-trifluorophenyl)propanoate (CAS 1630114-55-4)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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