3-Bromo-5-ethynylpyridin-2-amine CAS 1478858-45-5
| CAS No. | 1478858-45-5 |
| Molecular Formula | C7H5BrN2 |
| Molecular Weight | 197.03 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Bromo-5-ethynylpyridin-2-amine (CAS 1478858-45-5), molecular formula C7H5BrN2 and molecular weight 197.03 g/mol, is a CATO reference standard with documented purity and traceability.
3-Bromo-5-ethynylpyridin-2-amine (C7H5BrN2) contains a nitrile group, bromine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-Bromo-5-ethynylpyridin-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H5BrN2 |
| Molecular Weight | 197.03 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-1H-pyrrolo[3,2-c]pyridine (CAS 1000342-68-6)
- 6-Bromo-5-azaindole, 97% (CAS 1000342-71-1)
- 2-Bromo-5-cyano-6-picoline (CAS 1003711-39-4)
- 2-Bromo-1H-pyrrolo[2,3-b]pyridine (CAS 1083181-25-2)
- Methyl 2-bromo-4-hydroxybutanoate (CAS 111044-01-0)
- 2-Bromo-6-(cyanomethyl)pyridine (CAS 112575-11-8)
- 3-Bromo-3H-pyrrolo[2,3-b]pyridine (CAS 1160790-59-9)
- 5-Bromo-6-methylpicolinonitrile (CAS 1173897-86-3)
Recommended Standards
- 6-Bromo-3-pyridineacetonitrile (CAS 144873-99-4)
- 2-Bromopyrazolo[1,5-a]pyridine (CAS 1520497-11-3)
- 6-Bromo-1H-pyrrolo[2,3-b]pyridine (CAS 143468-13-7)
- 4-(Bromomethyl)picolinonitrile (CAS 153993-99-8)
- (E)-N'-Methyl-3-(trifluoromethyl)-N-[3-(trifluoromethyl)phenyl]benzene-1-carboximidamide (CAS 339028-34-1)
- 3-(5-Amino-1-(2-hydroxyethyl)-1H-benzo[d]imidazol-2-yl)propan-1-ol (CAS 700355-08-4)
- (Diethoxymethoxy)ethene (CAS 34712-46-4)
- 2-(3,4-Dichlorophenyl)pyrrolidine (CAS 298690-82-1)
- Quercetin 3-rutinoside 7-glucoside (CAS 30311-61-6)
- Methyl 1-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)phenyl]-1H-pyrazole-3-carboxylate (CAS 1707586-20-6)
- 2-(Aminomethyl)-5-(difluoromethyl)-4-(trifluoromethyl)pyridine-3-carboxaldehyde (CAS 1361700-99-3)
- 1-(3-Methylisoxazol-5-yl)butan-1-one (CAS 114402-52-7)
- Ethyl 5-chloro-1-(4-fluorophenyl)-1H-pyrazole-4-carboxylate (CAS 288252-75-5)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
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