1-(5-Chloro-2-hydroxybenzyl)pyrrolidine-3-carboxylic acid CAS 1479908-62-7
| CAS No. | 1479908-62-7 |
| Molecular Formula | C12H14ClNO3 |
| Molecular Weight | 255.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(5-Chloro-2-hydroxybenzyl)pyrrolidine-3-carboxylic acid.
1-(5-Chloro-2-hydroxybenzyl)pyrrolidine-3-carboxylic acid (CAS 1479908-62-7), molecular formula C12H14ClNO3 and molecular weight 255.70 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-(5-Chloro-2-hydroxybenzyl)pyrrolidine-3-carboxylic acid (C12H14ClNO3) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H14ClNO3 |
| Molecular Weight | 255.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 5-chloro-6-(cyclohexyloxy)pyridine-3-carboxylic acid (CAS 1008769-68-3)
- 1-Chloro-4-(4-pyridinylmethyl)phthalazine (CAS 101094-85-3)
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Recommended Standards
- 5-(3-Chlorophenyl)-3-phenylisoxazole (CAS 146537-67-9)
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- 1-(5-Aminopyridin-2-yl)piperidin-3-ol (CAS 939376-59-7)
- Methyl 3-(2-acetylphenyl)-5-fluorobenzoate (CAS 1820618-59-4)
- Calceolarioside A (CAS 84744-28-5)
- 4-Bromo-3,5-dicyclopropyl-1H-pyrazole (CAS 1629614-18-1)
- 2-((4-((2-(tert-Butoxy)-2-oxoethyl)amino)cyclohexyl)amino)acetic acid (CAS 1353964-43-8)
- 2-Butyl-4-chloro-6-methylpyrimidine (CAS 848499-42-3)
- Methyl 2-(3-fluorophenoxy)propanoate (CAS 1247636-15-2)
- 3-Chloro-1-(3-hydroxypiperidin-1-yl)propan-1-one (CAS 1153984-37-2)
- 1-Phenyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol (CAS 17579-12-3)
- Proinsulin C-Peptide (55-89) (human) (CAS 11097-48-6)
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