2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline CAS 1480939-99-8
| CAS No. | 1480939-99-8 |
| Molecular Formula | C10H12Cl2N2 |
| Molecular Weight | 231.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline.
CATO supplies 2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline (CAS 1480939-99-8), a certified reference material (molecular formula C10H12Cl2N2, MW 231.12 g/mol) for analytical method development and quality control.
The molecular framework of 2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline (C10H12Cl2N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2,4-Dichloro-6,6-dimethyl-5,6,7,8-tetrahydroquinazoline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H12Cl2N2 |
| Molecular Weight | 231.12 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Dichloro Standards
- 2,4-Dichloro-6-cyclohexylpyrimidine (CAS 1013110-01-4)
- 3,5-Dichloro-2-(piperidin-4-yl)pyridine (CAS 1260895-53-1)
- 4,6-Dichloro-2-cyclopropyl-5-isopropylpyrimidine (CAS 1341661-43-5)
- 1,4-DIchloro-2-(cyclopentyloxy)benzene (CAS 1394980-60-9)
- 2,6-Dichloro-3-(pyrolidin-1-ylmethyl)pyridine (CAS 1428234-65-4)
- 4,6-Dichloro-2-cyclobutyl-5-ethylpyrimidine (CAS 1466028-83-0)
- 2,4-Dichloro-8,8-dimethyl-5,6,7,8-tetrahydroquinazoline (CAS 1538445-96-3)
- 2,2-Dichloro-1,1,1-triethoxyethane (CAS 54567-92-9)
Recommended Standards
- (1-(2,5-Dichlorobenzyl)cyclopropyl)methanol (CAS 1470521-12-0)
- (1-(2,6-Dichlorobenzyl)cyclopropyl)methanol (CAS 1489588-09-1)
- (1-(2,4-Dichlorobenzyl)cyclopropyl)methanol (CAS 1498618-76-0)
- 4-Chloro-2-(1-chloroethyl)-6-cyclobutylpyrimidine (CAS 1427023-92-4)
- 5,5-Difluoro-1,3-Dioxane (CAS 36301-44-7)
- Sodium tetrachloroaurate (CAS 15189-51-2)
- 4-Propylchromane-4-carboxylic acid (CAS 1483837-16-6)
- 1,2,4-Benzenetricarboxylic Acid Benzyl Ester (CAS 16432-55-6)
- 4-bromo-3-(trifluoromethoxy)benzoic acid (CAS 1008769-87-6)
- 2-(((4-Ethylphenyl)amino)methyl)quinazolin-4(3H)-one (CAS 134577-51-8)
- Posaconazole Impurity 89 (CAS 183871-34-3(Free Base))
- 4-Chloro-6-phenyl-5H-pyrrolo[3,2-d]pyrimidin-2-amine (CAS 1253789-10-4)
- 5-(chloromethyl)-2,4-dimethyl-pyridine (CAS 856851-22-4)
- Acetyl-Tau Peptide (273-284) amide trifluoroacetate salt (CAS 1684399-52-7)
Why CATO?
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