2,2-Difluoro-2-(5-methylthiophen-2-yl)acetic acid CAS 1481644-05-6
| CAS No. | 1481644-05-6 |
| Molecular Formula | C7H6F2O2S |
| Molecular Weight | 192.18 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2,2-Difluoro-2-(5-methylthiophen-2-yl)acetic acid is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2,2-Difluoro-2-(5-methylthiophen-2-yl)acetic acid (CAS 1481644-05-6), molecular formula C7H6F2O2S and molecular weight 192.18 g/mol, is a CATO reference standard with documented purity and traceability.
2,2-Difluoro-2-(5-methylthiophen-2-yl)acetic acid (C7H6F2O2S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 2,2-Difluoro-2-(5-methylthiophen-2-yl)acetic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C7H6F2O2S |
| Molecular Weight | 192.18 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Difluoro Standards
- 2,2-Difluoro-2-(5-methylthiophen-3-yl)acetic acid (CAS 1462248-74-3)
- 1,3-Difluoro-5-(methylsulfonyl)benzene (CAS 171421-55-9)
- 1,2-Difluoro-4-(methylsulfonyl)benzene (CAS 424792-57-4)
- 1,4-Difluoro-2-(methylsulfonyl)benzene (CAS 236739-03-0)
- 2,4-Difluoro-1-(methylsulfonyl)benzene (CAS 236739-02-9)
- 7,7-Difluoro-6,7-dihydro-4H-pyrano[3,4-d]thiazol-2-amine (CAS 1391732-60-7)
- Methyl 4,4-difluoro-1-methylcyclohexanecarboxylate (CAS 1360568-90-6)
- methyl 2,2-difluoro-2-phenyl-acetate (CAS 56071-96-6)
Recommended Standards
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