4-Amino-2-(pyrrolidin-2-yl)butan-2-ol CAS 1481880-11-8
| CAS No. | 1481880-11-8 |
| Molecular Formula | C8H18N2O |
| Molecular Weight | 158.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-Amino-2-(pyrrolidin-2-yl)butan-2-ol is closely related to an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 4-Amino-2-(pyrrolidin-2-yl)butan-2-ol (CAS 1481880-11-8), a certified reference material (molecular formula C8H18N2O, MW 158.24 g/mol) for analytical method development and quality control.
The molecular framework of 4-Amino-2-(pyrrolidin-2-yl)butan-2-ol (C8H18N2O) is characterized by an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-Amino-2-(pyrrolidin-2-yl)butan-2-ol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H18N2O |
| Molecular Weight | 158.24 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 2 |
Related Amino Standards
- 4-Amino-N,N-diethylbutanamide (CAS 104970-81-2)
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- 2-Amino-N-hexylacetamide (CAS 132138-99-9)
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Recommended Standards
- 2-Methyl-1-(tetrahydro-2h-pyran-4-yl)propan-2-ol (CAS 1481265-09-1)
- 2-Amino-4-methylheptanamide (CAS 1485747-57-6)
- 1-(((2-Aminoethyl)amino)methyl)cyclopentan-1-ol (CAS 1479221-60-7)
- 3-(Piperidin-4-yloxy)propan-1-amine (CAS 1489328-85-9)
- 6,6-Dimethylhept-1-en-4-yn-3-ol (CAS 78629-20-6)
- 3-{[4-(1,1,3,3-Tetramethylbutyl)phenoxy]-methyl}piperidine hydrochloride (CAS 1219982-30-5)
- 2-Cyclopropyl-4,6-dimethylpyrimidine-5-carboxylic acid (CAS 548773-17-7)
- Rimegepant Impurity 133 (CAS CATO-C4X-2487133)
- 4-Bromo-N-(4-bromophenyl)-N-[4-(sec-butyl)phenyl]aniline (CAS 287976-94-7)
- 3-(Chloromethyl)benzene-1-sulfonyl fluoride (CAS 2090571-85-8)
- 1-(4-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-1,2,3-triazol-1-yl)phenyl)ethan-1-one (CAS 478041-19-9)
- 2-Chloro-3-(2-thiomethylphenyl)propiophenone (CAS 898780-16-0)
- 4-chloro-3-iodo-1-[(4-methoxyphenyl)methyl]-1H-pyrazolo[4,3-c]pyridine (CAS 1246349-97-2)
- Semaglutide impurity 47 (CAS CATO-C4X-222647)
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