2-Chloro-4-fluoro-5-iodophenol CAS 148254-33-5

Purity 97%+In StockPharmaceutical Standards
CAS No.148254-33-5
Molecular FormulaC6H3ClFIO
Molecular Weight272.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-Chloro-4-fluoro-5-iodophenol CAS 148254-33-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 272.44 g/mol gives 2-Chloro-4-fluoro-5-iodophenol distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

2-Chloro-4-fluoro-5-iodophenol (CAS 148254-33-5), molecular formula C6H3ClFIO and molecular weight 272.44 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 2-Chloro-4-fluoro-5-iodophenol (C6H3ClFIO) is characterized by a hydroxyl group, an ether linkage, fluorine/chlorine/iodine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 2-Chloro-4-fluoro-5-iodophenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC6H3ClFIO
Molecular Weight272.44 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF/Cl/I-containing

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