(1-Methyl-1h-1,2,4-triazol-5-yl)methanesulfonyl chloride CAS 1483075-12-2
| CAS No. | 1483075-12-2 |
| Molecular Formula | C4H6ClN3O2S |
| Molecular Weight | 195.63 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, (1-Methyl-1h-1,2,4-triazol-5-yl)methanesulfonyl chloride is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 195.63 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
(1-Methyl-1h-1,2,4-triazol-5-yl)methanesulfonyl chloride (CAS 1483075-12-2), molecular formula C4H6ClN3O2S and molecular weight 195.63 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (1-Methyl-1h-1,2,4-triazol-5-yl)methanesulfonyl chloride meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C4H6ClN3O2S |
| Molecular Weight | 195.63 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Recommended Standards
- 1-Ethyl-1H-1,2,3-triazole-4-sulfonyl chloride (CAS 1393568-12-1)
- 2-Ethyl-2H-1,2,3-triazole-4-sulfonyl chloride (CAS 1496511-51-3)
- 1-Ethyl-1h-1,2,3-triazole-5-sulfonyl chloride (CAS 1393543-91-3)
- 4-Chloro-1-methyl-1H-pyrazole-3-sulfonamide (CAS 154787-25-4)
- Methyl (R)-2-amino-3-(2,3,4-trifluorophenyl)propanoate (CAS 1213872-57-1)
- Ethyl 1-(aminomethyl)cyclobutane-1-carboxylate hydrochloride (CAS 1269021-92-2)
- Ethyl 7-Bromo-2,4-diethoxy-5H-pyrrolo[3,2-d]pyrimidine-6-carboxylate (CAS 20419-71-0)
- Pentoxyverine Impurity 14 (CAS CATO-C4X-227014)
- 3,3-Diethoxy-1,1,1-trifluoropropan-2-one (CAS 2169338-71-8)
- (3R)-1-methanesulfonylpyrrolidin-3-ol (CAS 1568109-24-9)
- Posaconazole Impurity 22(R,S,S,R) (CAS 1229428-90-3)
- 3-(3-Chloropropyl)-2-fluoro-4-iodopyridine (CAS 945600-05-5)
- 5-Methoxy-2-(4-(4-methoxyphenyl)-1H-pyrazol-3-yl)phenol (CAS 948901-10-8)
- Peptide Impurity 40 (CAS CATO-CPTD788840)
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