5-Fluoro-1H-indol-3-amine CAS 1483533-41-0
| CAS No. | 1483533-41-0 |
| Molecular Formula | C8H7FN2 |
| Molecular Weight | 150.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
5-Fluoro-1H-indol-3-amine (CAS 1483533-41-0) is a high-purity analytical reference standard with the molecular formula C8H7FN2 and a molecular weight of 150.15 g/mol.
Based on its molecular formula C8H7FN2, 5-Fluoro-1H-indol-3-amine contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 150.15 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
As a certified reference material (CRM), 5-Fluoro-1H-indol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H7FN2 |
| Molecular Weight | 150.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluoro Standards
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- 4-Fluoro-1H-indol-5-amine (CAS 1003858-66-9)
- 7-Fluoro-3-methyl-1h-indazole (CAS 1017682-73-3)
- 5-Fluoro-4-methyl-1H-indazole (CAS 105391-69-3)
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Recommended Standards
- 6-Fluoro-2,3-dihydro-1H-inden-1-one (CAS 1481-32-9)
- 2-Ethynyl-1-fluoro-3-methoxybenzene (CAS 1491067-02-7)
- rel-(2R,5R)-5-Hydroxy-1,3-oxathiolane-2-carboxylic acid (CAS 147027-04-1)
- (E)-3-(2-fluorophenyl)acrylaldehyde (CAS 149733-71-1)
- 3-((5,6,7,8-Tetrahydrobenzo[4,5]thieno[2,3-d]pyrimidin-4-yl)amino)propan-1-ol (CAS 40106-50-1)
- Alexidine DiHCl (CAS 1715-30-6)
- 4-(Pyridin-3-yl)butan-2-amine (CAS 88940-54-9)
- 2-(2-Acetamidoethyl)pyridine-4-sulfonic acid (CAS 88963-74-0)
- Ethyl2-oxo-3-phenylpiperidine-3-carboxylate (CAS 63378-71-2)
- 2-(Benzyloxy)-3-fluoroaniline (CAS 1184302-52-0)
- 2-Cyano-5-fluoro-nicotinic acid tert-butyl ester (CAS 2169295-82-1)
- Flubendazole EP Impurity A (CAS CATO-C4X-24384)
- (S)-N-((S)-1-(3-Bromo-5-fluorophenyl)-2-nitroethyl)-2-methylpropane-2-sulfinamide (CAS 1715032-46-4)
- Semaglutide impurity 67 (CAS CATO-C4X-222667)
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