Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate CAS 148356-79-0
| CAS No. | 148356-79-0 |
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate (CAS 148356-79-0), a certified reference material (molecular formula C11H10ClNO2, MW 223.66 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Methyl 5-chloro-1-methyl-1H-indole-2-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 223.66 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C11H10ClNO2 |
| Molecular Weight | 223.66 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Methyl Standards
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- 2-Chloro-4-(2-oxopyrrolidin-1-yl)benzaldehyde (CAS 1024204-74-7)
- 4-Chloro-2-(3-ethyl-1,2,4-oxadiazol-5-yl)aniline (CAS 1040345-45-6)
- Ethyl 6-chloro-1H-indole-5-carboxylate (CAS 1057076-52-4)
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- Methyl 7-chloro-2-methyl-1H-indole-3-carboxylate (CAS 1082470-30-1)
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Recommended Standards
- 4-Chloro-6,8-dimethoxyquinoline (CAS 148018-31-9)
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- 3-Chloro-1-isopropylpyrido[2,3-b]pyrazin-2(1H)-one (CAS 1443292-46-3)
- Ethyl (4-chlorophenyl)cyanoacetate (CAS 15032-43-6)
- 8-bromo-4-chloro-7-methoxy-1,6-naphthyridine (CAS 1434142-06-9)
- Pentamethyldisilane (CAS 812-15-7)
- 5-Fluoro-2-(1-piperidinyl)-4-pyrimidinylamine (CAS 247225-85-0)
- 2-(4-Bromophenyl)-5-(2,3-dimethoxybenzylidene)thiazolo[3,2-b][1,2,4]triazol-6(5H)-one (CAS 606950-26-9)
- Telmisartan Impurity 81 (CAS CATO-C4X-135981)
- 6-Chloro-5-iodo-2-(methylthio)pyrimidin-4-amine (CAS 500896-56-0)
- 5-Fluoro-2-(3-((R)-1-hydroxyethyl)-2,6-diisopropyl-5-propylpyridin-4-yl)phenol (CAS 1049703-56-1)
- 2-(2-Chloro-6-methylbenzofuran-3-yl)acetic acid (CAS 1420792-92-2)
- 1-(2,4-Difluorophenyl)-3,3-dimethylbutan-1-one (CAS 898764-94-8)
- Peptide 439 (CAS CATO-CPTD788439)
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