乌美溴铵杂质1 CAS 1484216-96-7
| CAS No. | 1484216-96-7 |
| Molecular Formula | C12H22ClNO3 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 乌美溴铵杂质1 (CAS 1484216-96-7), a pharmacopoeial impurity reference standard (molecular formula C12H22ClNO3HCl, MW 300.22 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of 乌美溴铵杂质1 (C12H22ClNO3HCl) is characterized by an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), 乌美溴铵杂质1 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H22ClNO3 HCl |
| Molecular Weight | 300.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 1.0 |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- (1E)-2,2-Dimethyl-3-(4-methylpiperazin-1-yl)-propanal oxime (CAS 1119452-80-0)
- (4-Hydroxy-3-nitrophenyl)(phenyl)methanone (CAS 5464-98-2)
- N-Boc-D-Thr(Bzl)-ol (CAS 168034-31-9)
- 4-Ethyl-3-methoxybenzophenone (CAS 82520-39-6)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
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