4-Chloro-2-(((2-hydroxy-2-methylpropyl)amino)methyl)phenol CAS 1484496-66-3
| CAS No. | 1484496-66-3 |
| Molecular Formula | C11H16ClNO2 |
| Molecular Weight | 229.70 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-Chloro-2-(((2-hydroxy-2-methylpropyl)amino)methyl)phenol (C11H16ClNO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
4-Chloro-2-(((2-hydroxy-2-methylpropyl)amino)methyl)phenol (CAS 1484496-66-3), molecular formula C11H16ClNO2 and molecular weight 229.70 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-2-(((2-hydroxy-2-methylpropyl)amino)methyl)phenol under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H16ClNO2 |
| Molecular Weight | 229.70 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- 4-Chloro-N-isopropyl-2,5-dimethoxyaniline (CAS 1019610-75-3)
- 4-Chloro-2-(((1-methoxypropan-2-yl)amino)methyl)phenol (CAS 1019629-10-7)
- 4-Chloro-2-(((3-methoxypropyl)amino)methyl)phenol (CAS 1042589-92-3)
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- 1-(3-Chloro-4-(2-methoxyethoxy)phenyl)ethan-1-amine (CAS 1226114-35-7)
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- N-(2-chloro-3,4-dimethoxybenzyl)ethanamine (CAS 1340422-18-5)
Recommended Standards
- 2-((1-(3-Chlorophenyl)ethyl)amino)propane-1,3-diol (CAS 1479749-11-5)
- N-[(E)-1-(4-chlorophenyl)methylidene]-N-(4-methylphenyl)amine (CAS 15485-32-2)
- 2-((1-(2-Chlorophenyl)ethyl)amino)propane-1,3-diol (CAS 1469094-63-0)
- 2-(2-((2-Chlorobenzyl)amino)ethoxy)ethan-1-ol (CAS 940357-47-1)
- 1,2,3,4-Tetrahydro-9-acridinecarboxylic acid (CAS 38186-54-8)
- (2,2'-Bipyridine)-5,5'-dicarbohydrazide (CAS 63361-67-1)
- 4-(2,4,6-trimethoxyphenyl)-1,2,3,6-tetrahydropyridine (CAS 923248-28-6)
- N-(5-{[(2-methylphenyl)methyl]sulfanyl}-1H-1,2,4-triazol-3-yl)benzenesulfonamide (CAS 866011-02-1)
- D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine HCl (CAS 135308-76-8)
- 5-Chloro-6-iodo-1H-benzo[d]imidazole-2(3H)-thione (CAS 1219741-21-5)
- 2-cyclopropyl-1-(oxiran-2-yl)propan-2-ol (CAS 2060048-60-2)
- 4-Methoxybenzene-1,2,3-triol (CAS 87997-30-6)
- 1H-Pyrazole-3-carboxamide, 4-[(2,6-dichlorobenzoyl)amino]-N-4-piperidinyl-, (methanesulfonate) (1:1) (CAS 902135-89-1)
- Liraglutide Impurity 14 TFA Salt (CAS CATO-C4X-199214)
Why CATO?
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