Donepezil Impurity 14 CAS 148517-82-2
| CAS No. | 148517-82-2 |
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Donepezil Impurity 14 (CAS 148517-82-2) is a certified pharmaceutical impurity reference standard with the molecular formula C11H12O4 and a molecular weight of 208.21 g/mol.
Based on its molecular formula C11H12O4, Donepezil Impurity 14 contains a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 208.21 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C11H12O4 |
| Molecular Weight | 208.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
Related Donepezil Standards
- Donepezil Impurity 16 (CAS 36517-91-6)
- Donepezil Aldehyde Impurity (CAS 22065-85-6)
- Donepezil EP impurity B (CAS 2107-69-9)
- Donepezil Intermediate 21 (CAS 6443-72-7)
- Donepezil Impurity 17 (CAS 127399-78-4)
- Donepezil Impurity 18 (CAS 90843-62-2)
- Donepezil Impurity 44 (CAS 1026443-48-0)
- Donepezil Impurity 45 (CAS 844694-83-3)
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