Methyl 5-fluoro-4-methylpicolinate CAS 148541-72-4
| CAS No. | 148541-72-4 |
| Molecular Formula | C8H8FNO2 |
| Molecular Weight | 169.15 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Methyl 5-fluoro-4-methylpicolinate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Methyl 5-fluoro-4-methylpicolinate (CAS 148541-72-4) is a high-purity analytical reference standard with the molecular formula C8H8FNO2 and a molecular weight of 169.15 g/mol.
Structurally, Methyl 5-fluoro-4-methylpicolinate (C8H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 5.0, corresponding to approximately 5 ring(s) or double-bond equivalent(s). With a molecular weight of 169.15 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C8H8FNO2 |
| Molecular Weight | 169.15 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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Recommended Standards
- Ethyl 5-fluoropicolinate (CAS 148541-70-2)
- 2-Fluoro-3-(pyridin-4-yl)propanoic acid (CAS 1505274-07-6)
- Methyl 2-Amino-3-fluorobenzoate (CAS 144851-82-1)
- 2-Fluoro-2-(6-methylpyridin-3-yl)acetic acid (CAS 1508152-80-4)
- 3-(Difluoromethyl)-4-fluoro-6-iodopyridin-2-amine (CAS 1804946-44-8)
- 5-Chloro-1,3-dimethyl-1h-pyrazole-4-sulfonamide (CAS 88398-46-3)
- (R)-1-(2-Chloropyridin-4-yl)ethan-1-ol (CAS 937399-97-8)
- 2-(2,4-Dichlorophenyl)-5-(pyridin-3-yl)-2,4-dihydro-3H-pyrazol-3-one (CAS 338757-78-1)
- (2S,4R)-4-Hydroxy-N-Phenylpyrrolidine-2-Carboxamide (CAS 84846-34-4)
- 4-Methyl-2-((2-methylbut-3-yn-2-yl)amino)benzoic acid (CAS 1343891-25-7)
- Cefazolin Impurity 44 (CAS 20198-75-8)
- Methyl 3-amino-4,4,4-trifluorobut-2-enoate (CAS 107638-19-7)
- 2-(Methylsulfinyl)phenol (CAS 1074-02-8)
- Insulin Degludec Impurity 18 (CAS CATO-C4X-215718)
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