Ethyl 2-((3,5-difluorophenyl)amino)-1,3-thiazole-4-carboxylate CAS 1485563-67-4
| CAS No. | 1485563-67-4 |
| Molecular Formula | C12H10F2N2O2S |
| Molecular Weight | 284.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Ethyl 2-((3,5-difluorophenyl)amino)-1,3-thiazole-4-carboxylate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Ethyl 2-((3,5-difluorophenyl)amino)-1,3-thiazole-4-carboxylate (CAS 1485563-67-4), a certified reference material (molecular formula C12H10F2N2O2S, MW 284.28 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, Ethyl 2-((3,5-difluorophenyl)amino)-1,3-thiazole-4-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 284.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C12H10F2N2O2S |
| Molecular Weight | 284.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 3-(Aminomethyl)pyrrolidine-2,5-dione hydrochloride (CAS 1799421-09-2)
- 3-[2-(Methylsulfonyl)-4-pyrimidinyl]pyrazolo[1,5-b]pyridazine (CAS 681432-34-8)
- 2-Hydrazinyl-N,N,6-trimethylpyrimidin-4-amine (CAS 63206-75-7)
- 4-Hydroxy-6-iodo-2-(trifluoromethoxy)pyridine-3-carbonyl chloride (CAS 1804745-44-5)
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- 2-oxaspiro[3.3]heptan-6-yl 4-methylbenzenesulfonate (CAS 2522927-67-7)
- 2-(((Cyclopropylmethyl)amino)methyl)-5-methoxyphenol (CAS 1248685-07-5)
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