Ethyl 4-((2-chloro-4-fluorobenzyl)oxy)benzoate CAS 1486972-05-7
| CAS No. | 1486972-05-7 |
| Molecular Formula | C16H14ClFO3 |
| Molecular Weight | 308.73 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-((2-chloro-4-fluorobenzyl)oxy)benzoate.
Ethyl 4-((2-chloro-4-fluorobenzyl)oxy)benzoate (CAS 1486972-05-7) is a high-purity analytical reference standard with the molecular formula C16H14ClFO3 and a molecular weight of 308.73 g/mol.
The molecular framework of Ethyl 4-((2-chloro-4-fluorobenzyl)oxy)benzoate (C16H14ClFO3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), Ethyl 4-((2-chloro-4-fluorobenzyl)oxy)benzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H14ClFO3 |
| Molecular Weight | 308.73 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl-containing |
Related Ethyl Standards
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- 1-{[3-Chloro-4-(trifluoromethoxy)phenyl]methyl}-1,4-diazepane (CAS 1240581-70-7)
- Ethyl 3-chloro-4-((2-fluorobenzyl)oxy)benzoate (CAS 1706428-94-5)
- Ethyl 3-chloro-4-((4-fluorobenzyl)oxy)benzoate (CAS 1706450-49-8)
- 2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)ethan-1-amine (CAS 338792-81-7)
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Recommended Standards
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- 3-Ethoxy-4-[(3-fluorobenzyl)oxy]benzoyl chloride (CAS 1160251-13-7)
- 4-((2-Chloro-4-fluorobenzyl)oxy)-3-ethoxybenzaldehyde (CAS 588713-64-8)
- TMI 1 (3S)-4-[[4-(2-Butyn-1-yloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-3-thiomorpholinecarboxamide 287403-39-8 (CAS 287403-39-8)
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- (±)-Cannabicyclol (CBL) (CAS 21366-63-2)
- 2-Bromo-N-(6-methoxybenzo[d]thiazol-2-yl)acetamide (CAS 98946-80-6)
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- 8-Chloro-2-methyl-[1,2,4]triazolo[1,5-a]pyridine (CAS 1892914-92-9)
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