(S)-2-Chloroacetyl-2-demethyl Thiocolchicine CAS 148731-67-3
| CAS No. | 148731-67-3 |
| Molecular Formula | C23H24ClNO6S |
| Molecular Weight | 477.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (S)-2-Chloroacetyl-2-demethyl Thiocolchicine is closely related to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (S)-2-Chloroacetyl-2-demethyl Thiocolchicine (CAS 148731-67-3), a certified reference material (molecular formula C23H24ClNO6S, MW 477.96 g/mol) for analytical method development and quality control.
Based on its molecular formula C23H24ClNO6S, (S)-2-Chloroacetyl-2-demethyl Thiocolchicine contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 477.96 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H24ClNO6S |
| Molecular Weight | 477.96 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related S Standards
- 3-(2-Chloroacetyl)-2-(1-hydroxyheptadecyl)quinazolin-4(3H)-one (CAS 917764-61-5)
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- N'1-(2-chloroacetyl)-2-{5-[3,5-di(trifluoromethyl)phenyl]-2H-1,2,3,4-tetraazol-2-yl}propanohydrazide (CAS 680214-90-8)
- 2-(1-(2-Chloroacetyl)-3-oxopiperazin-2-yl)-N-(4-phenoxyphenyl)acetamide (CAS 1306738-30-6)
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- n-[3-(2-chloroacetyl)-2,5-dimethyl-1h-pyrrol-1-yl]-3-methyl-4-oxo-3,4-dihydrophthalazine-1-carboxamide (CAS 790271-08-8)
Recommended Standards
- 2-Amino-9-(5-((6-chloro-2-methoxyacridin-9-yl)amino)pentyl)-1H-purin-6(9H)-one (CAS 103083-41-6)
- 3-{4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}-N-[2-(1H-indol-3-yl)ethyl]prop-2-enamide (CAS 946386-43-2)
- (S)-tert-butyl 3-((2-(4-amino-1,2,5-oxadiazol-3-yl)-4-chloro-1-ethyl-1H-imidazo[4,5-c]pyridin-7-yloxy)methyl)piperidine-1-carboxylate (CAS 937174-74-8)
- Ethyl 2-(2-{3-phenyl[(3-chlorophenyl)carbamoyl]amino}-1,3-thiazol-4-yl)benzoate (CAS 303150-08-5)
- Methyl 1,3-dioxo-1,3-dihydroisobenzofuran-5-carboxylate (CAS 2902-64-9)
- rel-(2R,5S)-Hexane-2,5-diol (CAS 38484-55-8)
- 7-Fluoro-6-methoxy-1(2H)-isoquinolinone (CAS 630422-98-9)
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- Varenicline Impurity 56 (CAS CATO-C4X-196256)
- 1,3-Benzodioxole-N-phthalimido DL-threo-Droxidopa (CAS 96614-52-7)
- (2R,3R)-rel-2-methyl-3-Piperidinecarboxylic acid methyl ester (CAS 2455600-70-9)
- 2-Cyclopropyl-3-(methylsulfonyl)-1H-pyrrole (CAS 1713174-56-1)
- N-(2,4-difluorophenyl)-1-methyl-5-(p-tolylthio)-3-(trifluoromethyl)-1H-pyrazole-4-carboxamide (CAS 158712-43-7)
- Semaglutide impurity 197 (CAS CATO-C4X-2226197)
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