2-Chloro-N-(tetrahydro-2H-pyran-4-yl)quinazolin-4-amine CAS 1487955-34-9
| CAS No. | 1487955-34-9 |
| Molecular Formula | C13H14ClN3O |
| Molecular Weight | 263.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, 2-Chloro-N-(tetrahydro-2H-pyran-4-yl)quinazolin-4-amine is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 263.72 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 2-Chloro-N-(tetrahydro-2H-pyran-4-yl)quinazolin-4-amine (CAS 1487955-34-9), a certified reference material (molecular formula C13H14ClN3O, MW 263.72 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H14ClN3O |
| Molecular Weight | 263.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloro Standards
- Ethyl 4-chloro-6-ethylquinoline-3-carboxylate (CAS 1019345-40-4)
- 2-(((3-Chloro-4-methoxyphenyl)amino)methyl)phenol (CAS 1019595-94-8)
- 6-Chloro-N-(4-methoxyphenethyl)pyridazin-3(2h)-imine (CAS 1040013-91-9)
- 4-Chloro-5-((2-methylphenethyl)amino)pyridazin-3(2h)-one (CAS 1062009-47-5)
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Recommended Standards
- Ethyl 5-(4-chloro-3-methylphenyl)-1H-pyrrole-3-carboxylate (CAS 1449692-01-6)
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- 1-Chloro-4-(4-morpholinyl)-2-naphthol (CAS 159596-04-0)
- (2,4-Dimethoxypyrimidin-5-yl)boronic acid (CAS 89641-68-9)
- (2E)-3-[4-(Benzyloxy)phenyl]-1-(morpholin-4-yl)prop-2-en-1-one (CAS 464907-66-2)
- 2-Hydroxy-N-isopentyl-4-methoxybenzamide (CAS 1019446-36-6)
- 5-Cyclopropoxy-N-methyl-6-nitropyridin-2-amine (CAS 1243393-95-4)
- 4-(Pyridin-4-ylcarbamoyl)-1H-imidazole-5-carboxylic acid (CAS 627470-18-2)
- 4-(4-Iodophenoxy)-2-(trifluoromethyl)quinazoline (CAS 339018-48-3)
- 3,5-Difluoro-2-(hexyloxy)benzaldehyde (CAS 1443343-83-6)
- tert-Butyl 2-(2-isopropoxypyridin-3-yl)piperidine-1-carboxylate (CAS 1352490-60-8)
- 2-Formyl-6-hydroxyisonicotinic acid (CAS 1289061-93-3)
- Tumor Targeted Pro-Apoptotic Peptide (CAS 1926163-30-5)
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