(2,4-Difluorophenyl)trimethylsilane CAS 148854-10-8
| CAS No. | 148854-10-8 |
| Molecular Formula | C9H12F2Si |
| Molecular Weight | 186.27 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
(2,4-Difluorophenyl)trimethylsilane (CAS 148854-10-8), molecular formula C9H12F2Si and molecular weight 186.27 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to fluorine substitution, (2,4-Difluorophenyl)trimethylsilane is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 186.27 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H12F2Si |
| Molecular Weight | 186.27 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO |
| Stability | May oxidize slowly on prolonged air exposure |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
Related Difluorophenyl Standards
- (3,5-Difluorophenyl)trimethylsilane (CAS 149130-47-2)
- 1-(3,4-Difluorophenyl)butan-1-ol (CAS 1179299-59-2)
- 1-(3,4-Difluorophenyl)-2-methylpropan-1-ol (CAS 1184394-61-3)
- 4-(3,4-Difluorophenyl)butan-1-ol (CAS 1215948-69-8)
- 4-(2,5-Difluorophenyl)butan-1-ol (CAS 1225768-50-2)
- 1-(3,5-Difluorophenyl)butan-1-ol (CAS 1226165-53-2)
- 4-(2,4-Difluorophenyl)butan-2-ol (CAS 1249054-04-3)
- 1-(2,5-Difluorophenyl)butan-2-ol (CAS 1250597-76-2)
Recommended Standards
- 1-Acetylpiperidine-2-carbothioamide (CAS 1485857-97-3)
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- 2-(((4-Methylthiazol-5-yl)methyl)amino)propan-1-ol (CAS 1497786-56-7)
- 2-(Methylthio)spiro[3.3]heptane-2-carboxylic acid (CAS 1485191-94-3)
- 3-(2,6-Dichlorophenyl)-5-[(E)-2-[(2,4-difluorophenyl)amino]ethenyl]-1,2-oxazole-4-carbonitrile (CAS 338402-62-3)
- 7-methyl-1H-imidazo[4,5-c]pyridin-4-amine (CAS 1031750-29-4)
- L-2-Aminothiazoline-4-carboxylic Acid (CAS 16899-18-6)
- 2-Methoxy-4-(2-oxoethyl)phenyl acetate (CAS 6391-59-9)
- Omidenepag isopropyl (CAS 1187451-19-9)
- Rivastigmine tartrate (CAS 129101-54-8)
- N-(3,4-Dichlorophenyl)-2-(2-mercapto-4-oxo-4,5-dihydro-1,3-thiazol-5-yl)acetamide (CAS 1142200-30-3)
- 3-(3-Chlorophenyl)-5-(2-chloropyridin-3-yl)-1,2,4-oxadiazole (CAS 1146522-21-5)
- 2'-Oxo-1',4'-dihydro-2'H-spiro[cyclopropane-1,3'-[1,5]naphthyridine]-7'-carboxylic acid (CAS 2765503-66-8)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
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