Ethyl 1-(4-chlorophenyl)cyclopropane-1-carboxylate CAS 148992-58-9
| CAS No. | 148992-58-9 |
| Molecular Formula | C12H13ClO2 |
| Molecular Weight | 224.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Ethyl 1-(4-chlorophenyl)cyclopropane-1-carboxylate (CAS 148992-58-9), molecular formula C12H13ClO2 and molecular weight 224.68 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system, Ethyl 1-(4-chlorophenyl)cyclopropane-1-carboxylate is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 224.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H13ClO2 |
| Molecular Weight | 224.68 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
Related Ethyl Standards
- 1-(4-Chlorophenyl)-4-methylpentane-1,3-dione (CAS 100119-43-5)
- 3-(4-Chlorophenyl)-4-methylpent-2-enoic acid (CAS 1017193-67-7)
- (2E)-3-(2-Chlorophenyl)-2-butenoic Acid Ethyl Ester (CAS 1056642-37-5)
- Ethyl 4-(4-chlorophenyl)but-2-enoate (CAS 1105703-73-8)
- 2-(2-Chlorophenyl)-1-(oxolan-2-yl)ethan-1-one (CAS 1179149-53-1)
- 1-(3-Chlorophenyl)hexane-1,3-dione (CAS 1247176-35-7)
- 2-(2-Chlorophenyl)-1-(tetrahydrofuran-3-yl)ethan-1-one (CAS 1249586-19-3)
- 1-(4-Chlorophenyl)-3-methylcyclobutane-1-carboxylic acid (CAS 1339332-79-4)
Recommended Standards
- 3-(3-Carboethoxyphenyl)-2-chloro-1-propene (CAS 148252-48-6)
- 2-(3-Chlorobenzyl)pent-4-enoic acid (CAS 1513186-01-0)
- 4-(3-chlorophenyl)-4-hydroxycyclohexan-1-one (CAS 1461708-22-4)
- (5-Chloro-2,3-dihydrobenzofuran-7-yl)(cyclopropyl)methanol (CAS 1566939-13-6)
- 3-hydroxyphenyl N-ethylcarbamate (CAS 108490-80-8)
- (R)-1-(2-Aminoethyl)-N-benzyl-N-cyclopropylpyrrolidin-3-amine (CAS 1354000-91-1)
- 1-Chloro-4-(difluoromethoxy)naphthalene (CAS 743451-75-4)
- 8-Hydroxyisoquinoline (CAS 3482-14-2)
- 3-(Anthracen-9-yl)-5-(tert-butyl)-4-nitroisoxazole (CAS 922139-06-8)
- 3-(Phenoxymethyl)-4-(p-tolyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 21358-14-5)
- rel-(1R,3R)-Methyl 3-aminocyclohexanecarboxylate (CAS 478694-53-0)
- 1-(Pyridin-2-ylmethyl)piperidine-2-carboxylic acid dihydrochloride (CAS 1027803-08-2)
- Isopropyl 3-[(chloroacetyl)amino]benzoate (CAS 6307-69-3)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com