5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole CAS 149045-79-4

Purity 97%+In StockPharmaceutical Standards
CAS No.149045-79-4
Molecular FormulaC7H2Cl2F2O2
Molecular Weight226.99 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole CAS 149045-79-4 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 226.99 g/mol gives 5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole (CAS 149045-79-4), a certified reference material (molecular formula C7H2Cl2F2O2, MW 226.99 g/mol) for analytical method development and quality control.

5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole (C7H2Cl2F2O2) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 5,6-Dichloro-2,2-difluorobenzo[d][1,3]dioxole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC7H2Cl2F2O2
Molecular Weight226.99 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1999
Halogen ContentF/Cl-containing

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