7-chloro-5-isopropyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid CAS 1490657-99-2
| CAS No. | 1490657-99-2 |
| Molecular Formula | C9H17ClN4O2 |
| Molecular Weight | 248.71 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 7-chloro-5-isopropyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
7-chloro-5-isopropyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 1490657-99-2), molecular formula C9H17ClN4O2 and molecular weight 248.71 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, 7-chloro-5-isopropyl-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 248.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C9H17ClN4O2 |
| Molecular Weight | 248.71 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- 5-Chloro-2-methoxy-N-(pyridin-3-ylmethyl)aniline (CAS 1019609-30-3)
- 2-Chloro-1-{1h,2h,3h,4h,5h-pyrido[4,3-b]indol-2-yl}ethan-1-one (CAS 1087784-16-4)
- 6-Chloro-N4-(1-phenylethyl)pyrimidine-4,5-diamine (CAS 112088-62-7)
- 6-Chloro-n4-(4-methylbenzyl)pyrimidine-2,4-diamine (CAS 122862-23-1)
- 6-Chloro-N4-(1-phenylethyl)pyrimidine-2,4-diamine (CAS 122862-38-8)
- 6-Chloro-2-methyl-N-((3-methylpyridin-2-yl)methyl)pyrimidin-4-amine (CAS 1333910-91-0)
- 7-Chloro-6-methyl-1,3,4,5-tetrahydrobenzo[b][1,6]naphthyridin-10(2H)-one (CAS 1338658-76-6)
- 2-Chloro-N-(3-cyanobenzyl)-N-cyclopropylacetamide (CAS 1353956-02-1)
Recommended Standards
- Vilazodone Impurity 6 (CAS 1451194-34-5)
- 8-(chloromethoxy)-5-nitro-quinoline (CAS 1501350-97-5)
- 4-chloro-5,6-dimethyl-N-(pyridin-2-ylmethyl)pyrimidin-2-amine (CAS 1450809-17-2)
- 2-Chloro-3-(piperazin-1-yl)quinoxaline (CAS 164670-46-6)
- (2S,4R)-1-(tert-butoxycarbonyl)-4-(4-cyanobenzyl)pyrrolidine-2-carboxylic acid (CAS 1217684-11-1)
- 4-Hydroxy-6-methoxy-1-methylquinolin-2(1H)-one (CAS 223668-09-5)
- (5-Chloro-1H-pyrrolo[2,3-c]pyridin-2-yl)methanol (CAS 867036-42-8)
- 4-Cyclopropoxy-2-ethylnicotinic acid (CAS 1243345-87-0)
- N-(6,7-Dihydro-6-Oxo-1H-Purin-2-yl)-2-methylpropanamide (CAS 21047-89-2)
- 1-methyl-4-nitropyrrole-2-carboxylic Acid (CAS 13138-78-8)
- 4-(Dimethylamino)-7-methyl-7h-pyrrolo[2,3-d]pyrimidine-6-carboxylic acid hydrochloride (CAS 1432681-71-4)
- 5-Bromo-4-chloro-8-fluoroquinazoline (CAS 1564693-03-3)
- 3-(4-Aminothieno[2,3-d]pyrimidin-6-yl)propanamide (CAS 885268-99-5)
- Anti-Inflammatory Peptide 2 (CAS 118850-72-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com