1-((3-Bromophenyl)thio)cyclobutane-1-carboxylic acid CAS 1491056-57-5
| CAS No. | 1491056-57-5 |
| Molecular Formula | C11H11BrO2S |
| Molecular Weight | 287.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-((3-Bromophenyl)thio)cyclobutane-1-carboxylic acid.
1-((3-Bromophenyl)thio)cyclobutane-1-carboxylic acid (CAS 1491056-57-5) is a high-purity analytical reference standard with the molecular formula C11H11BrO2S and a molecular weight of 287.17 g/mol.
The molecular framework of 1-((3-Bromophenyl)thio)cyclobutane-1-carboxylic acid (C11H11BrO2S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-((3-Bromophenyl)thio)cyclobutane-1-carboxylic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H11BrO2S |
| Molecular Weight | 287.17 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Sulfur Atoms | 1 |
Related Bromophenyl Standards
- 1-((2-Bromophenyl)thio)cyclobutane-1-carboxylic acid (CAS 1467612-49-2)
- 1-((4-Bromophenyl)thio)cyclobutane-1-carboxylic acid (CAS 1479699-91-6)
- 1-(4-Bromophenyl)-2-(oxetan-3-ylthio)ethan-1-one (CAS 1505121-35-6)
- 1-(3-Bromophenyl)-2-(oxetan-3-ylthio)ethan-1-one (CAS 1507010-90-3)
- 3-((4-Bromophenyl)thio)pentane-2,4-dione (CAS 314769-46-5)
- 2-(3-Bromophenyl)-5-methylimidazo[1,2-a]pyridine (CAS 1055025-30-3)
- 2-[(3-bromophenyl)methyl]-4-methoxybutanoic acid (CAS 1182757-92-1)
- 2-(2-Bromophenyl)-5-methyl-1H-benzo[d]imidazole (CAS 14225-84-4)
Recommended Standards
- (2-Bromo-4-fluorophenyl)(cyclohexyl)methanol (CAS 1443354-00-4)
- 4-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dihydropyridin-1(2H)-yl)pyrimidine (CAS 1605299-38-4)
- 1-(3-Bromo-5-fluorobenzyl)-4-methylpiperazine (CAS 1428065-36-4)
- 1-Ethyl-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indazol-3-amine (CAS 1626336-09-1)
- 2-{[(3-methylphenyl)carbamoyl]amino}acetic acid (CAS 133115-37-4)
- Methyl 3,3-dicyano-2,2-dimethylpropanoate (CAS 1228788-10-0)
- 1H-Pyrazolo[4,3-d]pyrimidine, 5-chloro-3-fluoro-7-methoxy-1-(2-methoxyethyl)- (CAS 2445848-22-4)
- 7-Chlorobenzo[d]thiazol-2-amine (CAS 20358-01-4)
- (r)-3-(1-Amino-2-hydroxyethyl)benzene-1,2-diol (CAS 1212965-50-8)
- tert-Butyl N-(pyrimidin-4-yl)carbamate (CAS 1820642-12-3)
- 2,3,5-Trichlorotoluene (CAS 56961-86-5)
- 9,9’-Spirobi[9H-fluorene] (CAS 159-66-0)
- 3-(Cyclohexylsulfamoyl)benzoic acid (CAS 313346-39-3)
- Insulin Lispro (CAS 133107-64-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com