1-(3-methyl-1H-pyrazol-5-yl)piperazine CAS 1491491-75-8
| CAS No. | 1491491-75-8 |
| Molecular Formula | C8H14N4 |
| Molecular Weight | 166.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(3-methyl-1H-pyrazol-5-yl)piperazine.
1-(3-methyl-1H-pyrazol-5-yl)piperazine (CAS 1491491-75-8) is a high-purity analytical reference standard with the molecular formula C8H14N4 and a molecular weight of 166.22 g/mol.
The molecular framework of 1-(3-methyl-1H-pyrazol-5-yl)piperazine (C8H14N4) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H14N4 |
| Molecular Weight | 166.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 4 |
Recommended Standards
- 1-[(1h-imidazol-1-yl)methyl]cyclopentan-1-ol (CAS 1489066-90-1)
- (1-(Cyclobutylmethyl)-1H-pyrazol-4-yl)methanol (CAS 1492566-89-8)
- (1-(Cyclobutylmethyl)-1H-1,2,3-triazol-4-yl)methanamine (CAS 1488790-96-0)
- 4-(Furan-2-yl)-1-methylpyrrolidin-3-amine (CAS 1493466-31-1)
- 6-Bromo-2-(methylsulfonyl)thiazolo[4,5-b]pyridine (CAS 194668-75-2)
- (4R, 2S)-4-Hydroxy-1-(9-phenyl-9H-fluoren-9-yl)-proline Methyl Ester (CAS 179990-59-1)
- 3-(azetidin-3-yloxy)isonicotinonitrile (CAS 1525233-36-6)
- Saxagliptin- (CAS 1370409-28-1)
- N,N'-(1,4-Phenylenebis(methanylylidene))bis(1-(furan-2-yl)methanamine) (CAS 105482-83-5)
- 5-Chloro-2,2-dimethylpentanenitrile (CAS 4207-54-9)
- 4-Acetyl-3,4-dihydro-1H-quinoxalin-2-one (CAS 120589-86-8)
- 4-Bromo-3-iodo-2H-pyrazolo[3,4-c]pyridine (CAS 1357946-92-9)
- Tetracycline EP Impurity B (CAS 6542-44-5)
- Semaglutide impurity 84 (CAS CATO-C4X-222684)
Why CATO?
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