CGP 55845 HCl CAS 149184-22-5
| CAS No. | 149184-22-5 |
| Molecular Formula | C18H22Cl2NO3P |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including CGP 55845 HCl.
CGP 55845 HCl (CAS 149184-22-5) is a high-purity analytical reference standard with the molecular formula C18H22Cl2NO3PHCl and a molecular weight of 438.71 g/mol.
Owing to a steroid core, an amide group, a phosphonate group, a hydroxyl group, an ether linkage, chlorine substitution, CGP 55845 HCl is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 438.71 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H22Cl2NO3P HCl |
| Molecular Weight | 438.71 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Recommended Standards
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- (R)-1-(2,5-dimethoxyphenyl)propan-2-ol (CAS 1188412-59-0)
- Fmoc-l-beta-homomethionine (CAS 266359-48-2)
- 1-(4-Hydroxy-3,5-dimethoxyphenyl)-2-(2-methoxyphenoxy)propane-1,3-diol (CAS 92409-34-2)
- Benzyl 4-formylcyclohexylcarbamate (CAS 170737-41-4)
- 1,2-Dimethyl-1H-pyrrolo[3,2-c]pyridine (CAS 680859-99-8)
- 3-(3-(Furan-2-yl)-1,2,4-oxadiazol-5-yl)propan-1-amine hydrochloride (CAS 1435804-19-5)
- Semaglutide impurity 39 (CAS CATO-C4X-222639)
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