Docetaxel Impurity 9 CAS 149198-47-0
| CAS No. | 149198-47-0 |
| Molecular Formula | C20H31NO4Si |
| Molecular Weight | 377.55 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Docetaxel Impurity 9 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Docetaxel Impurity 9 (CAS 149198-47-0) is a certified pharmaceutical impurity reference standard with the molecular formula C20H31NO4Si and a molecular weight of 377.55 g/mol.
Docetaxel Impurity 9 (C20H31NO4Si) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Docetaxel Impurity 9 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H31NO4Si |
| Molecular Weight | 377.55 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 1 |
Related Docetaxel Standards
- Docetaxel Impurity 84 (CAS CATO-C4X-161984)
- Docetaxel Impurity 38 (CAS 196404-55-4)
- Docetaxel Impurity 69 (CAS 155396-69-3)
- Docetaxel Impurity 71 (CAS 157580-39-7)
- Docetaxel impurity 83 (CAS CATO-C4X-161983)
- Docetaxel Impurity 64 (CAS CATO-C4X-161964)
- Docetaxel Impurity 15 Sodium Salt (CAS 223134-87-0)
- Docetaxel Impurity 42 (CAS 670254-71-4)
Recommended Standards
- (3S,4R)-tert-Butyl 2-oxo-4-phenyl-3-((triethylsilyl)oxy)azetidine-1-carboxylate (CAS 944154-74-9)
- Ethyl 7-chloro-6-iodo-4-oxo-1,4-dihydroquinoline-3-carboxylate (CAS 1021913-01-8)
- cis-tert-Butyl 2-oxo-4-phenyl-3-((triethylsilyl)oxy)azetidine-1-carboxylate (CAS 149107-85-7)
- ((5-Chloro-7-iodoquinolin-8-yl)oxy)methyl acetate (CAS 88350-18-9)
- Rimegepant Impurity 39 (CAS CATO-C4X-248739)
- (6R,7S)-Ceftriaxone Impurity (CAS CATO-C4X-116316)
- Rivaroxaban Impurity 76 (CAS 2305917-61-5)
- Methyl 4-(hydroxy(4-methoxyphenyl)methyl)benzoate (CAS 256475-05-5)
- 1-((5-Fluorothiophen-2-yl)methyl)piperazine (CAS 1245771-49-6)
- (S)-7,8-difluorochroman-4-amine (CAS 1213161-36-4)
- 5-Bromo-3-chloro-2-iodobenzotrifluoride (CAS 1027512-67-9)
- 4-(2,4-Dimethylheptan-2-yl)phenol (CAS 174305-83-0)
- 2-(Methylsulfanyl)-7-[(Z)-2-phenylethenyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 1164564-47-9)
- Semaglutide impurity 92 (CAS CATO-C4X-222692)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com