5-Bromo-1-(2-fluorobenzyl)pyridin-2(1h)-one CAS 1492148-75-0
| CAS No. | 1492148-75-0 |
| Molecular Formula | C12H9BrFNO |
| Molecular Weight | 282.11 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 282.11 g/mol gives 5-Bromo-1-(2-fluorobenzyl)pyridin-2(1h)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Bromo-1-(2-fluorobenzyl)pyridin-2(1h)-one (CAS 1492148-75-0) is a high-purity analytical reference standard with the molecular formula C12H9BrFNO and a molecular weight of 282.11 g/mol.
5-Bromo-1-(2-fluorobenzyl)pyridin-2(1h)-one (C12H9BrFNO) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-Bromo-1-(2-fluorobenzyl)pyridin-2(1h)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H9BrFNO |
| Molecular Weight | 282.11 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 1 |
Related Bromo Standards
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Recommended Standards
- 4-Bromo-2-(3-fluorophenoxy)-phenylamine (CAS 1484153-49-2)
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