3-Amino-5-(3-pyridyl)-1H-pyrazole CAS 149246-87-7
| CAS No. | 149246-87-7 |
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 3-Amino-5-(3-pyridyl)-1H-pyrazole (CAS 149246-87-7), a certified reference material (molecular formula C8H12N4, MW 164.21 g/mol) for analytical method development and quality control.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 3-Amino-5-(3-pyridyl)-1H-pyrazole is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 164.21 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C8H12N4 |
| Molecular Weight | 164.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Nitrogen Atoms | 4 |
Related Amino Standards
- 3-Amino-1-isobutyl-1H-pyrazole-4-carbonitrile (CAS 122799-97-7)
- 2-(4-Amino-3,5-dimethyl-1h-pyrazol-1-yl)propanenitrile (CAS 1249489-34-6)
- 2-(Amino(cyclopropyl)methyl)pyrimidin-4-amine (CAS 1340418-32-7)
- 3-Amino-1-tert-butyl-1h-pyrazole-4-carbonitrile (CAS 1375161-32-2)
- 2-(4-Amino-3-methyl-pyrazol-1-yl)-2-methyl-propanenitrile (CAS 1393100-52-1)
- 3-Amino-5-(tert-butyl)-1H-pyrazole-4-carbonitrile (CAS 141458-80-2)
- 5-Amino-1-(tert-butyl)-1H-pyrazole-4-carbonitrile (CAS 158001-28-6)
- 3-Amino-5-(4-pyridyl)-1H-pyrazole (CAS 91912-53-7)
Recommended Standards
- 2,2-Dimethyl-4-(1h-1,2,4-triazol-1-yl)butanenitrile (CAS 1490391-62-2)
- (1-(Pyrimidin-4-yl)azetidin-3-yl)methanamine (CAS 1497802-78-4)
- N-(azetidin-3-yl)-2-methylpyrimidin-4-amine (CAS 1485463-70-4)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridine-2-carboximidamide (CAS 1508348-58-0)
- 2,2-dioxo-2λ⁶-thiaspiro[3.3]heptan-6-one (CAS 1936319-38-8)
- (4-(tert-Butyl)phenyl)(2-iodophenyl)methanone 951889-75-1 (CAS 951889-75-1)
- 5-Hydroxybenzoxazole (CAS 180716-28-3)
- 4-(2-FLuoro-4-nitrobenzyl)morpholine (CAS 503160-30-3)
- 3-Cyclopropyl-thiophene (CAS 29576-51-0)
- N1-Isopropyl-N1-((1-methylpiperidin-3-yl)methyl)ethane-1,2-diamine (CAS 1353980-69-4)
- 2-Chloro-5-cyclopropylpyrimidine (CAS 166740-44-9)
- 2-Methoxy-1,3,4-thiadiazole hydrochloride (CAS 1332529-61-9)
- 1-(1H-Indazol-5-yl)ethanol (CAS 181820-37-1)
- Autoinducing Peptide I trifluoroacetate salt (CAS 200010-29-3)
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