4-[(2-Naphthyloxy)methyl]benzoic acid CAS 149288-37-9
| CAS No. | 149288-37-9 |
| Molecular Formula | C18H14O3 |
| Molecular Weight | 278.30 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-[(2-Naphthyloxy)methyl]benzoic acid (CAS 149288-37-9), molecular formula C18H14O3 and molecular weight 278.30 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[(2-Naphthyloxy)methyl]benzoic acid (C18H14O3) is characterized by a steroid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), 4-[(2-Naphthyloxy)methyl]benzoic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H14O3 |
| Molecular Weight | 278.30 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
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Recommended Standards
- Methyl 1-(2-methyl-4-nitrophenyl)piperidine-4-carboxylate (CAS 1456260-41-5)
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- Tert-butyl ((1-(2-hydroxyethyl)piperidin-4-yl)methyl)carbamate (CAS 1353981-34-6)
- 3,5-Diiodo-2-methylpyridin-4-amine (CAS 1227266-99-0)
- tert-Butyl 3-hydroxy-7,8-dihydro-1,6-naphthyridine-6(5H)-carboxylate (CAS 625098-86-4)
- 2-(3-Amino-4-methylpyridin-2-yl)propan-2-ol (CAS 2407073-26-9)
- (S)-2-(4-bromo-3-chlorophenyl)pyrrolidine (CAS 1213861-78-9)
- 6-(2-Fluoro-5-methylphenoxy)hexanenitrile (CAS 1443354-39-9)
- tert-Butyl 3-((tert-butyldimethylsilyl)oxy)-6-hydroxyhexahydro-4H-furo[3,2-b]pyrrole-4-carboxylate (CAS 1544206-88-3)
- 4-Chloro-3-hydroxy-1-methyl-1H-pyrazole-5-carboxylic acid (CAS 1551493-58-3)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
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