4-Methyl-2-phenyl-5-(trifluoromethyl)thiazole CAS 1492900-85-2
| CAS No. | 1492900-85-2 |
| Molecular Formula | C11H8F3NS |
| Molecular Weight | 243.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
4-Methyl-2-phenyl-5-(trifluoromethyl)thiazole (CAS 1492900-85-2), molecular formula C11H8F3NS and molecular weight 243.25 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C11H8F3NS, 4-Methyl-2-phenyl-5-(trifluoromethyl)thiazole contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 243.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H8F3NS |
| Molecular Weight | 243.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Recommended Standards
- (R)-4-(difluoromethyl)-2-methoxy-5-(pyrrolidin-2-yl)phenol (CAS 1446946-77-5)
- 4-(3,3,3-Trifluoropropyl)thiomorpholine-3-carboxylic acid (CAS 1544381-45-4)
- 1-Methyl-4-(2-methyl-2H-tetrazol-5-yl)-1H-pyrazole-5-sulfonamide (CAS 139481-22-4)
- Ethyl 2-(difluoromethyl)-6-isopropylnicotinate (CAS 1708288-64-5)
- 2-(Methylsulfonyl)-3-nitropyridine (CAS 56825-29-7)
- (E)-(1-{1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-methyl-1H-imidazol-4-yl}ethylidene)amino 4-chlorobenzoate (CAS 306976-45-4)
- 1,2-Di(pyridin-2-yl)ethane (CAS 4916-40-9)
- N-(thiophen-2-ylmethyl)-1H-indazol-5-amine (CAS 864422-25-3)
- 5-Bromo-2-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1211588-96-3)
- 2,3-Dimethylimidazo[1,2-a]pyridine-7-carbaldehyde (CAS 1263378-46-6)
- (S)-2-amino-6-(benzyloxy)-6-oxohexanoic acid (CAS 38658-15-0)
- 1-(3-Aminopropyl)cyclopropan-1-ol (CAS 321917-01-5)
- Pimavanserin Impurity 30 (CAS 359878-47-0（free base）)
- Protein Kinase C (19-36) Peptide (CAS 113731-96-7)
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