| CAS No. | 1493593-37-5 |
| Molecular Formula | C8H5N5OS |
| Molecular Weight | 219.22 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Compared with other compounds in its class, the molecular weight of 219.22 g/mol gives 4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,2,5-oxadiazol-3-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,2,5-oxadiazol-3-amine (CAS 1493593-37-5), molecular formula C8H5N5OS and molecular weight 219.22 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,2,5-oxadiazol-3-amine (C8H5N5OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 4-{[1,3]thiazolo[5,4-b]pyridin-2-yl}-1,2,5-oxadiazol-3-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
| Molecular Formula | C8H5N5OS |
| Molecular Weight | 219.22 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |