1-(5-bromopyridin-2-yl)-1H-pyrazol-5-amine CAS 1494496-85-3
| CAS No. | 1494496-85-3 |
| Molecular Formula | C8H7BrN4 |
| Molecular Weight | 239.07 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(5-bromopyridin-2-yl)-1H-pyrazol-5-amine.
CATO supplies 1-(5-bromopyridin-2-yl)-1H-pyrazol-5-amine (CAS 1494496-85-3), a certified reference material (molecular formula C8H7BrN4, MW 239.07 g/mol) for analytical method development and quality control.
1-(5-bromopyridin-2-yl)-1H-pyrazol-5-amine (C8H7BrN4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-(5-bromopyridin-2-yl)-1H-pyrazol-5-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H7BrN4 |
| Molecular Weight | 239.07 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related bromopyridin Standards
- 1-(3-Bromopyridin-2-yl)-1h-pyrazol-4-amine (CAS 1247866-28-9)
- 1-(5-Bromopyridin-2-yl)-1h-pyrazol-3-amine (CAS 1249078-80-5)
- 3-(6-Bromopyridin-2-yl)pentanenitrile (CAS 1956370-73-2)
- 5-(5-Bromopyridin-3-yl)-4h-1,2,4-triazol-3-amine (CAS 1152581-72-0)
- 1-(3-Bromopyridin-2-yl)-1h-1,2,4-triazol-3-amine (CAS 1249324-60-4)
- N-(3-bromopyridin-2-yl)-2-cyanoacetamide (CAS 1507694-97-4)
- N-(5-bromopyridin-2-yl)-2-cyanoacetamide (CAS 157141-57-6)
- 2-(4-Bromopyridin-2-yl)-5-methyl-1,3,4-oxadiazole (CAS 380380-59-6)
Recommended Standards
- 3-Bromo-5-methyl[1,6]naphthyridin-2(1H)-one (CAS 147293-25-2)
- 4-Bromo-1-(pyridin-2-yl)-1H-pyrazol-5-amine (CAS 150187-17-0)
- 5-Bromo-7-methylbenzofuran-2-carbaldehyde (CAS 1466305-03-2)
- 5-(3-Bromophenyl)isoxazol-3-amine (CAS 1506846-84-9)
- Oxazole-5-carbothioamide (CAS 885274-32-8)
- Bisoxatina (CAS 17692-24-9)
- OS-3-106, >98% (HPLC) (CAS 1580000-17-4)
- N-(5-Bromo-4-(trifluoromethyl)pyridin-2-yl)pivalamide (CAS 1447945-74-5)
- tert-Butyl N-[(3R,5R)-5-fluoropiperidin-3-yl]carbamate (CAS 1363378-07-7)
- (R)-Di-tert-butyl 2-(4-chlorophenyl)piperazine-1,4-dicarboxylate (CAS 769944-52-7)
- N-[3-[(2E)-3-(Dimethylamino)-1-oxo-2-propen-1-yl]phenyl]-N-ethyl-formamide (CAS 1227694-93-0)
- 3-Chloro-5-fluoro-1H-pyrrolo[2,3-b]pyridine (CAS 1190321-60-8)
- N-(2,4-difluorophenyl)-4-methyl-2-(3-(trifluoromethyl)phenyl)thiazole-5-carboxamide (CAS 320420-97-1)
- Peptide-GMF (CAS CATO-CPTD788469)
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