3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine CAS 1494547-79-3
| CAS No. | 1494547-79-3 |
| Molecular Formula | C11H12F3NO |
| Molecular Weight | 231.21 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine.
3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine (CAS 1494547-79-3) is a high-purity analytical reference standard with the molecular formula C11H12F3NO and a molecular weight of 231.21 g/mol.
The molecular framework of 3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine (C11H12F3NO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(4-(Trifluoromethyl)phenoxy)cyclobutan-1-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H12F3NO |
| Molecular Weight | 231.21 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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