2-(3-Bromo-4-fluorobenzylidene)malononitrile CAS 149550-26-5
| CAS No. | 149550-26-5 |
| Molecular Formula | C10H4BrFN2 |
| Molecular Weight | 251.05 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 2-(3-Bromo-4-fluorobenzylidene)malononitrile (C10H4BrFN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
2-(3-Bromo-4-fluorobenzylidene)malononitrile (CAS 149550-26-5), molecular formula C10H4BrFN2 and molecular weight 251.05 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(3-Bromo-4-fluorobenzylidene)malononitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H4BrFN2 |
| Molecular Weight | 251.05 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 2 |
Related Bromo Standards
- 4-Bromo-6-fluoroquinoline-3-carbonitrile (CAS 1260657-16-6)
- Methyl 4-bromo-1-(2-fluoroethyl)-1H-pyrazole-3-carboxylate (CAS 1429418-54-1)
- 4-Bromo-2-(2-fluoro-ethyl)-2h-pyrazole-3-carboxylic acid methyl ester (CAS 1429419-53-3)
- 4-Bromo-2-fluorobenzalmalononitrile (CAS 502496-31-3)
- 5-Bromo-7-fluoroquinoline-8-carbonitrile (CAS 2181780-00-5)
- 6-Bromo-3-fluoroquinoline-5-carbonitrile (CAS 2836225-04-6)
- 5-Bromo-2-nitrothiophene-3-carboxamide (CAS 1093878-20-6)
- 5-Bromo-2-nitrothiophene-3-carbaldehyde oxime (CAS 1201924-03-9)
Recommended Standards
- 1-(5-Boronopyrimidin-2-yl)piperidine-4-carboxylic acid (CAS 1515925-20-8)
- BT2F-Br (CAS 1557037-07-6)
- Methyl 3-(4-boronobenzamido)propionate (CAS 957034-76-3)
- Methyl 3-(3-boronobenzamido)propionate (CAS 957034-72-9)
- N-((4-Aminophenyl)sulfonyl)-N-(6-methoxypyridazin-3-yl)acetamide (CAS 3568-43-2)
- 5-((Trans-4-aminocyclohexyl)oxy)isoquinoline-4-carbonitrile (CAS 651308-53-1)
- 2-Amino-5-methyl-4-pyrimidinol (CAS 15981-91-6)
- (R)-tert-Butyl 3-((2-chloro-6-methylpyrimidin-4-yl)amino)pyrrolidine-1-carboxylate (CAS 1261234-31-4)
- 3-Hydroxy-2,3-dimethylbutan-2-yl hydrogen (4-(4-methoxyphenyl)thiazol-5-yl)boronate (CAS 2223053-39-0)
- 5-(Hydroxymethyl)pyrimidine-2-carbonitrile (CAS 1956366-36-1)
- 1-Azakenpaullone (CAS 676596-65-9)
- 1-(Pyridin-3-yl)hexan-1-amine (CAS 60289-66-9)
- Pitavastatin-d4 Sodium Salt (CAS 574705-92-3)
- [14-31]-Semaglutide (CAS CATO-C4X-2226262)
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