2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline CAS 1496-40-8
| CAS No. | 1496-40-8 |
| Molecular Formula | C12H15F3N2 |
| Molecular Weight | 244.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline (CAS 1496-40-8) is a high-purity analytical reference standard with the molecular formula C12H15F3N2 and a molecular weight of 244.26 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution, 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 244.26 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H15F3N2 |
| Molecular Weight | 244.26 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Piperidin Standards
- 3-(Piperidin-1-yl)-5-(trifluoromethyl)aniline (CAS 1041053-53-5)
- 2-(piperidin-4-yl)-5-(trifluoromethyl)aniline (CAS 1260823-98-0)
- 4-(Piperidin-1-yl)-2-(trifluoromethyl)aniline (CAS 954260-57-2)
- 2-(Piperidin-1-yl)-5-(trifluoromethyl)aniline hydrochloride 27429-68-1 (CAS 27429-68-1)
- 1-(Piperidin-1-ylmethyl)indoline-2,3-dione (CAS 13129-69-6)
- 4-Phenyl-3-(piperidin-4-yl)-1H-1,2,4-triazol-5(4H)-one (CAS 1508385-99-6)
- 2-(Piperidin-4-ylmethyl)isoindoline-1,3-dione (CAS 153747-01-4)
- 4-(Piperidin-1-yl)-1H-pyrrolo[2,3-b]pyridine-5-carboxamide (CAS 920959-46-2)
Recommended Standards
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