5-Chloro-2-(2-cyclopropylethoxy)benzene-1-sulfonyl chloride CAS 1496690-60-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1496690-60-8
Molecular FormulaC11H12Cl2O3S
Molecular Weight295.18 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Chloro-2-(2-cyclopropylethoxy)benzene-1-sulfonyl chloride CAS 1496690-60-8 chemical structure

Description

The occurrence of 5-Chloro-2-(2-cyclopropylethoxy)benzene-1-sulfonyl chloride is closely related to a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Chloro-2-(2-cyclopropylethoxy)benzene-1-sulfonyl chloride (CAS 1496690-60-8) is a high-purity analytical reference standard with the molecular formula C11H12Cl2O3S and a molecular weight of 295.18 g/mol.

The molecular framework of 5-Chloro-2-(2-cyclopropylethoxy)benzene-1-sulfonyl chloride (C11H12Cl2O3S) is characterized by a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC11H12Cl2O3S
Molecular Weight295.18 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)5.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentCl-containing
Sulfur Atoms1

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