3-(2-(Trifluoromethyl)phenyl)-1H-pyrazole CAS 149739-52-6
| CAS No. | 149739-52-6 |
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 212.17 g/mol gives 3-(2-(Trifluoromethyl)phenyl)-1H-pyrazole distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(2-(Trifluoromethyl)phenyl)-1H-pyrazole (CAS 149739-52-6), a certified reference material (molecular formula C10H7F3N2, MW 212.17 g/mol) for analytical method development and quality control.
The molecular framework of 3-(2-(Trifluoromethyl)phenyl)-1H-pyrazole (C10H7F3N2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(2-(Trifluoromethyl)phenyl)-1H-pyrazole under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C10H7F3N2 |
| Molecular Weight | 212.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 8-(Trifluoromethyl)quinolin-6-amine (CAS 1080640-91-0)
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- 8-(Trifluoromethyl)quinolin-2-amine (CAS 1092304-80-7)
- 7-(Trifluoromethyl)quinolin-2-amine (CAS 113508-12-6)
- 2-[1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]acetic acid (CAS 1154762-97-6)
- 6-(Trifluoromethyl)naphthalen-2-ol (CAS 116511-74-1)
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Recommended Standards
- 5-[3-(Trifluoromethyl)phenyl]-1h-pyrazole (CAS 149739-48-0)
- 4-(2,2,2-Trifluoroethyl)tetrahydro-2h-pyran-4-carboxylic acid (CAS 1499121-57-1)
- 3-(3-Fluoro-4-methoxyphenyl)-2-oxopropanoic acid (CAS 1493985-60-6)
- 2-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-fluoroacetic acid (CAS 1521641-63-3)
- 11-Bromotetraphene (CAS 1263386-46-4)
- 5-Methyl-3-[4-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-1,2,4-oxadiazole (CAS 1056456-23-5)
- 3-Bromo-1-trityl-1H-pyrazolo[4,3-b]pyridine (CAS 633328-34-4)
- Bis(3-chloro-4-fluorophenyl)(hydroxy)borane (CAS 872495-46-0)
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Why CATO?
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