Clemastine fumarate CAS 14976-57-9
| CAS No. | 14976-57-9 |
| Molecular Formula | C21H26ClNO |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Clemastine fumarate (CAS 14976-57-9), molecular formula C21H26ClNOC4H4O4 and molecular weight 459.97 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, Clemastine fumarate (C21H26ClNOC4H4O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 459.97 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C21H26ClNO C4H4O4 |
| Molecular Weight | 459.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1961 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Clemastine Standards
- Clemastine Impurity 27 (CAS 10095-17-7)
- Clemastine EP Impurity A(Mixture of Diastereomers) (CAS 108825-05-4)
- Clemastine Impurity 28 (CAS 1333340-87-6)
- Clemastine EP Impurity B (CAS 1352549-49-5)
- Clemastine (CAS 15686-51-8)
- Clemastine Impurity 26 (CAS 171296-35-8)
- Clemastine Impurity 4 (CAS 20763-27-3)
- Clemastine Fumarate Impurity 2 (CAS 530-48-3)
Recommended Standards
- 2-Methylcyclopent-1-ene-1-carboxylic acid (CAS 67209-77-2)
- (S)-1-Amino-2,3-dihydro-1H-indene-5-carboxylic acid (CAS 903630-36-4)
- N-(4-BROMO-2-CHLOROPHENYL)-3-CHLOROPROPANAMIDE (CAS 1098343-13-5)
- L-malic acid-1-<SUP>13</SUP>C (CAS 180991-05-3)
- N,N-Diallyl-4-methylbenzenesulfonamide (CAS 50487-72-4)
- (3S)-Methyl 4-benzyl-6-(iodomethyl)-6-methylmorpholine-3-carboxylate (CAS 1001054-44-9)
- N-((S)-1-((S)-2-Aminopropanoyl)pyrrolidin-3-yl)-N-isopropylacetamide (CAS 1401667-88-6)
- Methyl 3-(4-iodo-1H-pyrazol-1-yl)propanoate (CAS 1175275-82-7)
- 1-(2-(5-Bromo-2-methoxyphenyl)-4-methylthiazol-5-yl)ethan-1-one (CAS 877820-49-0)
- Semaglutide Impurity 147 (CAS CATO-C4X-2226147)
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