1-Bromo-4-(tert-butyldimethylsilyloxy)-3-methoxybenzene CAS 149777-72-0

Description

Compared with other compounds in its class, the molecular weight of 317.29 g/mol gives 1-Bromo-4-(tert-butyldimethylsilyloxy)-3-methoxybenzene distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

1-Bromo-4-(tert-butyldimethylsilyloxy)-3-methoxybenzene (CAS 149777-72-0), molecular formula C13H21BrO2Si and molecular weight 317.29 g/mol, is a CATO reference standard with documented purity and traceability.

1-Bromo-4-(tert-butyldimethylsilyloxy)-3-methoxybenzene (C13H21BrO2Si) contains a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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