Ethyl 4-((2-fluorobenzyl)oxy)benzoate CAS 1498060-48-2
| CAS No. | 1498060-48-2 |
| Molecular Formula | C16H15FO3 |
| Molecular Weight | 274.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-((2-fluorobenzyl)oxy)benzoate.
Ethyl 4-((2-fluorobenzyl)oxy)benzoate (CAS 1498060-48-2) is a high-purity analytical reference standard with the molecular formula C16H15FO3 and a molecular weight of 274.29 g/mol.
Ethyl 4-((2-fluorobenzyl)oxy)benzoate (C16H15FO3) contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H15FO3 |
| Molecular Weight | 274.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
Related Ethyl Standards
- Methyl 6-(((4-fluorobenzyl)amino)methyl)picolinate (CAS 1201663-99-1)
- 1-(4-((4-Fluorobenzyl)oxy)-3-methoxyphenyl)ethan-1-one (CAS 890092-12-3)
- 3-(3-Fluorobenzyl)-4-(3-fluorophenyl)butan-2-one (CAS 73931-67-6)
- N-(4-Fluorobenzyl)-4-nitrobenzamide (CAS 331434-68-5)
- N-(4-Fluorobenzyl)-2-isobutoxyaniline (CAS 1040694-48-1)
- 4-((4-Fluorobenzyl)oxy)-3-nitrobenzaldehyde (CAS 175136-18-2)
- 2-((3-Fluorobenzyl)oxy)-5-nitrobenzaldehyde (CAS 219539-49-8)
- 5-(4-fluorobenzyl)pyridine-2,3-dicarboxylic acid (CAS 862508-85-8)
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