o-Phenylene Phosphorochloridate CAS 1499-17-8

Purity 97%+In StockPharmaceutical Standards
CAS No.1499-17-8
Molecular FormulaC6H4ClO3P
Molecular Weight190.52 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

o-Phenylene Phosphorochloridate CAS 1499-17-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 190.52 g/mol gives o-Phenylene Phosphorochloridate distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

o-Phenylene Phosphorochloridate (CAS 1499-17-8), molecular formula C6H4ClO3P and molecular weight 190.52 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of o-Phenylene Phosphorochloridate (C6H4ClO3P) is characterized by a phosphonate group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H4ClO3P
Molecular Weight190.52 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, keep sealed and dry, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, ethanol, DMSO, water
StabilityMay oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)4.5
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1957
Halogen ContentCl-containing

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