(3R,4S)-3,4-bis(trifluoromethyl)pyrrolidine CAS 1500153-52-5

Purity 97%+In StockPharmaceutical Standards
CAS No.1500153-52-5
Molecular FormulaC6H7F6N
Molecular Weight207.12 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3R,4S)-3,4-bis(trifluoromethyl)pyrrolidine CAS 1500153-52-5 chemical structure

Description

The occurrence of (3R,4S)-3,4-bis(trifluoromethyl)pyrrolidine is closely related to fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (3R,4S)-3,4-bis(trifluoromethyl)pyrrolidine (CAS 1500153-52-5), a certified reference material (molecular formula C6H7F6N, MW 207.12 g/mol) for analytical method development and quality control.

Structurally, (3R,4S)-3,4-bis(trifluoromethyl)pyrrolidine (C6H7F6N) contains fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 1.0, corresponding to approximately 1 ring(s) or double-bond equivalent(s). With a molecular weight of 207.12 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC6H7F6N
Molecular Weight207.12 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)1.0
CAS Registry Year (est.)1992
Halogen ContentF-containing
Nitrogen Atoms1

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