N-(3-chlorobenzyl)-6,7,8-trimethoxyquinazolin-4-amine CAS 150450-08-1
| CAS No. | 150450-08-1 |
| Molecular Formula | C18H18ClN3O3 |
| Molecular Weight | 359.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
N-(3-chlorobenzyl)-6,7,8-trimethoxyquinazolin-4-amine (CAS 150450-08-1) is a high-purity analytical reference standard with the molecular formula C18H18ClN3O3 and a molecular weight of 359.81 g/mol.
The molecular framework of N-(3-chlorobenzyl)-6,7,8-trimethoxyquinazolin-4-amine (C18H18ClN3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H18ClN3O3 |
| Molecular Weight | 359.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related N Standards
- N-(4-chlorobenzyl)-6,7,8-trimethoxyquinazolin-4-amine (CAS 150450-07-0)
- 2-(4-Chlorobenzyl)-4-(2,4-dimethoxyphenyl)-5-methyl-2,4-dihydro-3H-1,2,4-triazol-3-one (CAS 861206-39-5)
- 1-(4-Chlorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1105244-01-6)
- 2-((3-Chlorobenzyl)oxy)-5-(2-methylthiazol-4-yl)benzoic acid (CAS 1416342-70-5)
- 2-((4-Chlorobenzyl)thio)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 339097-73-3)
- 2-((4-Chlorobenzyl)thio)-N-(2-methoxyethyl)quinazolin-4-amine (CAS 422532-96-5)
- Ethyl 4-(2-chlorobenzyl)-3-methyl-4H-benzo[b][1,4]thiazine-2-carboxylate (CAS 339098-19-0)
- 1-(4-Chlorobenzyl)-3-(3,4-dichlorophenyl)-1-methoxyurea (CAS 149282-25-7)
Recommended Standards
- (3-Chloro-4-methylphenyl)(4-(4-nitrophenyl)piperazin-1-yl)methanone (CAS 431996-53-1)
- 3-((3-Chlorophenoxy)methyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 1188296-52-7)
- (E)-6-Chloro-3-(pyridin-2-yl)-2-styrylquinazolin-4(3H)-one (CAS 708212-97-9)
- trans-1-[(Benzyloxy)carbonyl]-4-(4-chlorophenyl)pyrrolidine-3-carboxylic acid (CAS 2140264-20-4)
- methyl 2-amino-4-(1-piperidyl)butanoate (CAS 1270692-69-7)
- 3-Methyl-2-(5-(methylamino)-1,3,4-thiadiazol-2-yl)-7,8-dihydropyrrolo[1,2-a]thieno[2,3-d]pyrimidin-4(6H)-one (CAS 883276-11-7)
- (4-Amino-1,2,5-oxadiazol-3-yl)(4-fluorophenyl)methanone (CAS 924871-43-2)
- Tert-butyl 3-(4-hydroxy-1H-pyrazol-1-yl)azetidine-1-carboxylate (CAS 2270907-87-2)
- (3-Cyanophenyl)methanesulfonyl chloride (CAS 56106-01-5)
- (S)-1,1,1-trifluoroheptan-2-ol (CAS 130025-35-3)
- N,N-Dimethyl-2-((3-phenylquinolin-2-yl)oxy)ethanamine (CAS 89110-98-5)
- Methyl 3-amino-1-cyano-1-phenyl-1H-indene-2-carboxylate (CAS 116617-18-6)
- (2,4-Difluorobenzyl)(ethyl)sulfane (CAS 1443339-46-5)
- D-Ile12-Tirzepatide (CAS CATO-CPTD788921)
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